Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1468978..1469212 | Replicon | chromosome |
| Accession | NZ_CP026803 | ||
| Organism | Shigella flexneri strain 89-141 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1469108..1469211 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1468978..1469212 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C1P88_RS07530 | 1465533..1466195 | - | 663 | WP_000944269.1 | exodeoxyribonuclease X | - |
| C1P88_RS07535 | 1466219..1466875 | - | 657 | Protein_1441 | carbon-nitrogen hydrolase family protein | - |
| C1P88_RS07540 | 1466977..1467207 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| C1P88_RS07545 | 1467346..1467720 | + | 375 | Protein_1443 | CopC domain-containing protein YobA | - |
| C1P88_RS07550 | 1467724..1468596 | + | 873 | WP_000879271.1 | copper homeostasis membrane protein CopD | - |
| C1P88_RS07555 | 1468609..1468950 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 1468978..1469212 | - | 235 | - | - | Antitoxin |
| - | 1469108..1469211 | + | 104 | - | - | Toxin |
| C1P88_RS07560 | 1469333..1470371 | - | 1039 | Protein_1446 | phage integrase Arm DNA-binding domain-containing protein | - |
| C1P88_RS07565 | 1470337..1470618 | - | 282 | WP_005127484.1 | excisionase | - |
| C1P88_RS07570 | 1470725..1470913 | - | 189 | WP_000276807.1 | DUF1187 family protein | - |
| - | 1470729..1470907 | + | 179 | NuclAT_0 | - | - |
| - | 1470729..1470907 | + | 179 | NuclAT_0 | - | - |
| - | 1470729..1470907 | + | 179 | NuclAT_0 | - | - |
| - | 1470729..1470907 | + | 179 | NuclAT_0 | - | - |
| C1P88_RS07575 | 1470964..1471275 | - | 312 | WP_000334730.1 | hypothetical protein | - |
| C1P88_RS07580 | 1471335..1472503 | + | 1169 | WP_000747032.1 | IS3-like element IS911 family transposase | - |
| C1P88_RS07585 | 1472509..1473267 | + | 759 | Protein_1451 | IS3-like element IS600 family transposase | - |
| C1P88_RS07590 | 1473311..1473796 | + | 486 | Protein_1452 | DUF4376 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T96059 NZ_CP026803:1469108-1469211 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT96059 NZ_CP026803:c1469212-1468978 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
