Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1794055..1794289 | Replicon | chromosome |
| Accession | NZ_CP026799 | ||
| Organism | Shigella flexneri strain NCTC 9728 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1794185..1794288 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1794055..1794289 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C1P82_RS09170 | 1790611..1791273 | - | 663 | WP_000944267.1 | exodeoxyribonuclease X | - |
| C1P82_RS09175 | 1791297..1791953 | - | 657 | Protein_1746 | carbon-nitrogen hydrolase family protein | - |
| C1P82_RS09180 | 1792055..1792285 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| C1P82_RS09185 | 1792424..1792798 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| C1P82_RS09190 | 1792802..1793673 | + | 872 | Protein_1749 | copper homeostasis membrane protein CopD | - |
| C1P82_RS09195 | 1793686..1794027 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 1794055..1794289 | - | 235 | - | - | Antitoxin |
| - | 1794185..1794288 | + | 104 | - | - | Toxin |
| C1P82_RS09200 | 1794420..1795496 | - | 1077 | WP_001189100.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| C1P82_RS09205 | 1795462..1795743 | - | 282 | WP_134807616.1 | excisionase | - |
| C1P82_RS09210 | 1795860..1797016 | - | 1157 | Protein_1753 | IS3 family transposase | - |
| C1P82_RS09215 | 1797117..1797305 | - | 189 | WP_000276807.1 | DUF1187 family protein | - |
| - | 1797121..1797299 | + | 179 | NuclAT_0 | - | - |
| - | 1797121..1797299 | + | 179 | NuclAT_0 | - | - |
| - | 1797121..1797299 | + | 179 | NuclAT_0 | - | - |
| - | 1797121..1797299 | + | 179 | NuclAT_0 | - | - |
| C1P82_RS09220 | 1797356..1798453 | - | 1098 | WP_001173296.1 | AAA family ATPase | - |
| C1P82_RS09225 | 1798483..1798755 | - | 273 | WP_001277358.1 | host-nuclease inhibitor protein Gam | - |
| C1P82_RS24110 | 1798733..1799155 | - | 423 | WP_001249968.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 1737648..1808784 | 71136 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T96020 NZ_CP026799:1794185-1794288 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGGCCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGGCCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT96020 NZ_CP026799:c1794289-1794055 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGCCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGCCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
