Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4522190..4522424 | Replicon | chromosome |
| Accession | NZ_CP026793 | ||
| Organism | Shigella flexneri strain 74-1170 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4522191..4522294 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4522190..4522424 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C1P81_RS23005 | 4517636..4518103 | - | 468 | Protein_4420 | DNA-binding transcriptional regulator PgrR | - |
| C1P81_RS23010 | 4518167..4518477 | + | 311 | Protein_4421 | transposase | - |
| C1P81_RS23015 | 4518520..4519715 | - | 1196 | Protein_4422 | IS3 family transposase | - |
| C1P81_RS23020 | 4519770..4520618 | + | 849 | Protein_4423 | IS3-like element IS600 family transposase | - |
| C1P81_RS23025 | 4520735..4521016 | + | 282 | WP_005127484.1 | excisionase | - |
| C1P81_RS27060 | 4520982..4522059 | + | 1078 | Protein_4425 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 4522190..4522424 | + | 235 | - | - | Antitoxin |
| - | 4522191..4522294 | - | 104 | - | - | Toxin |
| C1P81_RS23040 | 4522452..4522793 | - | 342 | WP_000976476.1 | YebY family protein | - |
| C1P81_RS23045 | 4522806..4523678 | - | 873 | Protein_4427 | copper homeostasis membrane protein CopD | - |
| C1P81_RS23050 | 4523682..4524056 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| C1P81_RS23055 | 4524195..4524425 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| C1P81_RS23060 | 4524527..4525183 | + | 657 | Protein_4430 | carbon-nitrogen hydrolase family protein | - |
| C1P81_RS23065 | 4525207..4525869 | + | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 4518167..4527926 | 9759 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T95980 NZ_CP026793:c4522294-4522191 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT95980 NZ_CP026793:4522190-4522424 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
