Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 443274..443508 | Replicon | chromosome |
| Accession | NZ_CP026788 | ||
| Organism | Shigella flexneri 2a strain ATCC 29903 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 443404..443507 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 443274..443508 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C1P79_RS02470 | 439829..440491 | - | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
| C1P79_RS02475 | 440515..441171 | - | 657 | Protein_453 | carbon-nitrogen hydrolase family protein | - |
| C1P79_RS02480 | 441273..441503 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| C1P79_RS02485 | 441642..442016 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| C1P79_RS02490 | 442020..442892 | + | 873 | Protein_456 | copper homeostasis membrane protein CopD | - |
| C1P79_RS02495 | 442905..443246 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 443274..443508 | - | 235 | - | - | Antitoxin |
| - | 443404..443507 | + | 104 | - | - | Toxin |
| C1P79_RS26090 | 443639..444716 | - | 1078 | Protein_458 | phage integrase Arm DNA-binding domain-containing protein | - |
| C1P79_RS02510 | 444682..444963 | - | 282 | WP_005127484.1 | excisionase | - |
| C1P79_RS02515 | 445080..445928 | - | 849 | Protein_460 | IS3-like element IS600 family transposase | - |
| C1P79_RS02520 | 445983..447178 | + | 1196 | Protein_461 | IS3 family transposase | - |
| C1P79_RS02525 | 447221..447531 | - | 311 | Protein_462 | transposase | - |
| C1P79_RS02530 | 447595..448062 | + | 468 | Protein_463 | DNA-binding transcriptional regulator PgrR | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T95933 NZ_CP026788:443404-443507 [Shigella flexneri 2a]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT95933 NZ_CP026788:c443508-443274 [Shigella flexneri 2a]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
