Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 542093..542326 | Replicon | chromosome |
| Accession | NZ_CP026786 | ||
| Organism | Shigella dysenteriae strain NCTC 9718 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 542093..542196 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 542093..542326 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C1P65_RS03135 | 537858..537977 | - | 120 | WP_001131442.1 | hypothetical protein | - |
| C1P65_RS03140 | 537938..538123 | - | 186 | WP_023637031.1 | hypothetical protein | - |
| C1P65_RS03155 | 539161..539442 | + | 282 | WP_078164586.1 | excisionase | - |
| C1P65_RS03160 | 539557..540253 | - | 697 | Protein_589 | IS1 family transposase | - |
| C1P65_RS03165 | 540330..541486 | + | 1157 | WP_134801760.1 | IS3-like element IS600 family transposase | - |
| C1P65_RS03170 | 541531..541971 | + | 441 | Protein_591 | tyrosine-type recombinase/integrase | - |
| - | 542093..542196 | - | 104 | - | - | Toxin |
| - | 542093..542326 | + | 234 | - | - | Antitoxin |
| C1P65_RS03175 | 542354..542695 | - | 342 | WP_000976472.1 | YebY family protein | - |
| C1P65_RS03180 | 542708..543580 | - | 873 | WP_000879288.1 | copper homeostasis membrane protein CopD | - |
| C1P65_RS03185 | 543584..543958 | - | 375 | WP_000168738.1 | CopC domain-containing protein YobA | - |
| C1P65_RS03190 | 544097..544327 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| C1P65_RS03195 | 544429..545085 | + | 657 | WP_000896381.1 | carbon-nitrogen hydrolase family protein | - |
| C1P65_RS03200 | 545109..545771 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T95910 NZ_CP026786:c542196-542093 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 234 bp
>AT95910 NZ_CP026786:542093-542326 [Shigella dysenteriae]
AAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATA
AAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT
AAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATA
AAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT
