Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3144126..3144359 Replicon chromosome
Accession NZ_CP026784
Organism Shigella dysenteriae strain 80-547

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3144126..3144229 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3144126..3144359 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5B79_RS17180 3139889..3140008 - 120 WP_001131442.1 hypothetical protein -
C5B79_RS17185 3139969..3140154 - 186 WP_023637031.1 hypothetical protein -
C5B79_RS17190 3140346..3141041 - 696 Protein_3203 IS1-like element IS1N family transposase -
C5B79_RS17200 3141193..3141474 + 282 WP_134806426.1 excisionase -
C5B79_RS17205 3141589..3142285 - 697 Protein_3205 IS1 family transposase -
C5B79_RS17210 3142362..3143518 + 1157 WP_134801760.1 IS3-like element IS600 family transposase -
C5B79_RS17215 3143564..3144004 + 441 Protein_3207 tyrosine-type recombinase/integrase -
- 3144126..3144229 - 104 - - Toxin
- 3144126..3144359 + 234 - - Antitoxin
C5B79_RS17220 3144387..3144728 - 342 WP_134802023.1 YebY family protein -
C5B79_RS17225 3144741..3145613 - 873 WP_000879288.1 copper homeostasis membrane protein CopD -
C5B79_RS17230 3145617..3145991 - 375 WP_000168738.1 CopC domain-containing protein YobA -
C5B79_RS17235 3146130..3146360 + 231 WP_000916763.1 DNA polymerase III subunit theta -
C5B79_RS17240 3146462..3147118 + 657 WP_000896381.1 carbon-nitrogen hydrolase family protein -
C5B79_RS17245 3147142..3147804 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T95894 NZ_CP026784:c3144229-3144126 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 234 bp

>AT95894 NZ_CP026784:3144126-3144359 [Shigella dysenteriae]
AAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATA
AAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References