Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3312907..3313140 Replicon chromosome
Accession NZ_CP026782
Organism Shigella dysenteriae strain 08-3380

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3313037..3313140 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3312907..3313140 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1P64_RS18460 3309462..3310124 - 663 WP_000944256.1 exodeoxyribonuclease X -
C1P64_RS18465 3310148..3310804 - 657 WP_000896381.1 carbon-nitrogen hydrolase family protein -
C1P64_RS18470 3310906..3311136 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C1P64_RS18475 3311275..3311649 + 375 WP_000168738.1 CopC domain-containing protein YobA -
C1P64_RS18480 3311653..3312525 + 873 WP_000879288.1 copper homeostasis membrane protein CopD -
C1P64_RS18485 3312538..3312879 + 342 WP_134802023.1 YebY family protein -
- 3312907..3313140 - 234 - - Antitoxin
- 3313037..3313140 + 104 - - Toxin
C1P64_RS18490 3313262..3313702 - 441 Protein_3358 tyrosine-type recombinase/integrase -
C1P64_RS18500 3314981..3315677 + 697 Protein_3360 IS1 family transposase -
C1P64_RS18505 3315792..3316073 - 282 WP_134806426.1 excisionase -
C1P64_RS18515 3316225..3316920 + 696 Protein_3362 IS1-like element IS1N family transposase -
C1P64_RS18520 3317112..3317297 + 186 WP_023637031.1 hypothetical protein -
C1P64_RS18525 3317258..3317377 + 120 WP_001131442.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T95875 NZ_CP026782:3313037-3313140 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 234 bp

>AT95875 NZ_CP026782:c3313140-3312907 [Shigella dysenteriae]
AAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATA
AAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References