Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 953069..953302 Replicon chromosome
Accession NZ_CP026780
Organism Shigella dysenteriae strain 53-3937

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 953199..953302 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 953069..953302 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1P63_RS05270 949624..950286 - 663 WP_000944256.1 exodeoxyribonuclease X -
C1P63_RS05275 950310..950966 - 657 WP_000896381.1 carbon-nitrogen hydrolase family protein -
C1P63_RS05280 951068..951298 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C1P63_RS05285 951437..951811 + 375 WP_000168738.1 CopC domain-containing protein YobA -
C1P63_RS05290 951815..952687 + 873 WP_000879288.1 copper homeostasis membrane protein CopD -
C1P63_RS05295 952700..953041 + 342 WP_000976472.1 YebY family protein -
- 953069..953302 - 234 - - Antitoxin
- 953199..953302 + 104 - - Toxin
C1P63_RS05300 953424..953864 - 441 Protein_985 tyrosine-type recombinase/integrase -
C1P63_RS05310 955143..955840 + 698 Protein_987 IS1 family transposase -
C1P63_RS05315 955955..956236 - 282 WP_078164586.1 excisionase -
C1P63_RS05325 956388..957082 + 695 WP_134802562.1 IS1-like element IS1N family transposase -
C1P63_RS05330 957274..957459 + 186 WP_023637031.1 hypothetical protein -
C1P63_RS05335 957420..957539 + 120 WP_001131442.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T95851 NZ_CP026780:953199-953302 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 234 bp

>AT95851 NZ_CP026780:c953302-953069 [Shigella dysenteriae]
AAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATA
AAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References