Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3304076..3304309 | Replicon | chromosome |
| Accession | NZ_CP026777 | ||
| Organism | Shigella dysenteriae strain 69-3818 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3304206..3304309 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3304076..3304309 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C5C01_RS17945 | 3300632..3301294 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| C5C01_RS17950 | 3301318..3301974 | - | 657 | WP_000896381.1 | carbon-nitrogen hydrolase family protein | - |
| C5C01_RS17955 | 3302076..3302306 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| C5C01_RS17960 | 3302445..3302819 | + | 375 | WP_000168738.1 | CopC domain-containing protein YobA | - |
| C5C01_RS17965 | 3302823..3303694 | + | 872 | Protein_3366 | copper homeostasis membrane protein CopD | - |
| C5C01_RS17970 | 3303707..3304048 | + | 342 | WP_000976472.1 | YebY family protein | - |
| - | 3304076..3304309 | - | 234 | - | - | Antitoxin |
| - | 3304206..3304309 | + | 104 | - | - | Toxin |
| C5C01_RS17975 | 3304431..3304871 | - | 441 | Protein_3368 | tyrosine-type recombinase/integrase | - |
| C5C01_RS17985 | 3306150..3306846 | + | 697 | Protein_3370 | IS1 family transposase | - |
| C5C01_RS17990 | 3306961..3307242 | - | 282 | WP_078164586.1 | excisionase | - |
| C5C01_RS18000 | 3307394..3308088 | + | 695 | WP_134802562.1 | IS1-like element IS1N family transposase | - |
| C5C01_RS18005 | 3308280..3308465 | + | 186 | WP_023637031.1 | hypothetical protein | - |
| C5C01_RS18010 | 3308426..3308545 | + | 120 | WP_001131442.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | iroN / iroN / iroE / iroD / iroD / iroC / iroB / rcsA / ipaH9.8 / ipaH9.8 / fliC / fliA / flhD / flhC / motA / motB / motB / flhA | 3135706..3327694 | 191988 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T95836 NZ_CP026777:3304206-3304309 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 234 bp
>AT95836 NZ_CP026777:c3304309-3304076 [Shigella dysenteriae]
AAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATA
AAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT
AAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATA
AAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT
