Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 434685..434919 | Replicon | chromosome |
| Accession | NZ_CP026776 | ||
| Organism | Shigella flexneri strain 98-3193 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 434815..434918 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 434685..434919 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C1P84_RS02440 | 431240..431902 | - | 663 | WP_000944271.1 | exodeoxyribonuclease X | - |
| C1P84_RS02445 | 431926..432582 | - | 657 | Protein_450 | carbon-nitrogen hydrolase family protein | - |
| C1P84_RS02450 | 432684..432914 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| C1P84_RS02455 | 433053..433427 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| C1P84_RS02460 | 433431..434303 | + | 873 | Protein_453 | copper homeostasis membrane protein CopD | - |
| C1P84_RS02465 | 434316..434657 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 434685..434919 | - | 235 | - | - | Antitoxin |
| - | 434815..434918 | + | 104 | - | - | Toxin |
| C1P84_RS23555 | 435050..436125 | - | 1076 | Protein_455 | phage integrase Arm DNA-binding domain-containing protein | - |
| C1P84_RS02480 | 436091..436372 | - | 282 | WP_005127484.1 | excisionase | - |
| C1P84_RS02485 | 436489..437337 | - | 849 | Protein_457 | IS3-like element IS600 family transposase | - |
| C1P84_RS02490 | 437392..438601 | + | 1210 | Protein_458 | IS3 family transposase | - |
| C1P84_RS02495 | 438644..438954 | - | 311 | Protein_459 | transposase | - |
| C1P84_RS02500 | 439018..439485 | + | 468 | Protein_460 | DNA-binding transcriptional regulator PgrR | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 381575..445642 | 64067 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T95805 NZ_CP026776:434815-434918 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT95805 NZ_CP026776:c434919-434685 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
