95759

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 536716..536950 Replicon chromosome
Accession NZ_CP026768
Organism Shigella flexneri Y strain 93-3063

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 536846..536949 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 536716..536950 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1P87_RS02850 533271..533933 - 663 WP_000944270.1 exodeoxyribonuclease X -
C1P87_RS02855 533957..534613 - 657 Protein_535 carbon-nitrogen hydrolase family protein -
C1P87_RS02860 534715..534945 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C1P87_RS02865 535084..535458 + 375 WP_000168747.1 CopC domain-containing protein YobA -
C1P87_RS02870 535513..536334 + 822 Protein_538 copper homeostasis membrane protein CopD -
C1P87_RS02875 536347..536688 + 342 WP_000976476.1 YebY family protein -
- 536716..536950 - 235 - - Antitoxin
- 536846..536949 + 104 - - Toxin
C1P87_RS02880 537081..538157 - 1077 Protein_540 phage integrase Arm DNA-binding domain-containing protein -
C1P87_RS02885 538123..538404 - 282 WP_005127484.1 excisionase -
C1P87_RS02890 539417..539418 - 2 WP_134796927.1 IS3-like element IS600 family transposase -
C1P87_RS02895 539777..539965 - 189 WP_000276807.1 DUF1187 family protein -
- 539781..539959 + 179 NuclAT_0 - -
- 539781..539959 + 179 NuclAT_0 - -
- 539781..539959 + 179 NuclAT_0 - -
- 539781..539959 + 179 NuclAT_0 - -
C1P87_RS02900 540016..541113 - 1098 WP_134798213.1 AAA family ATPase -
C1P87_RS02905 541143..541415 - 273 WP_001277358.1 host-nuclease inhibitor Gam family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T95759 NZ_CP026768:536846-536949 [Shigella flexneri Y]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT95759 NZ_CP026768:c536950-536716 [Shigella flexneri Y]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References