Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4386369..4386603 Replicon chromosome
Accession NZ_CP026766
Organism Shigella boydii strain 59-248

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4386499..4386602 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4386369..4386603 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1P58_RS22740 4381786..4382927 + 1142 Protein_4306 prolyl oligopeptidase family serine peptidase -
C1P58_RS22745 4382924..4383586 - 663 WP_000944260.1 exodeoxyribonuclease X -
C1P58_RS22750 4383610..4384266 - 657 WP_000011642.1 carbon-nitrogen hydrolase family protein -
C1P58_RS22755 4384368..4384598 - 231 WP_000916761.1 DNA polymerase III subunit theta -
C1P58_RS22760 4384737..4385111 + 375 WP_134802482.1 CopC domain-containing protein YobA -
C1P58_RS22765 4385115..4385987 + 873 WP_000879302.1 copper homeostasis membrane protein CopD -
C1P58_RS22770 4386000..4386341 + 342 WP_000976476.1 YebY family protein -
- 4386369..4386603 - 235 - - Antitoxin
- 4386499..4386602 + 104 - - Toxin
C1P58_RS22775 4386734..4387261 - 528 Protein_4313 tyrosine-type recombinase/integrase -
C1P58_RS22785 4388694..4389796 + 1103 Protein_4315 IS3 family transposase -
C1P58_RS22790 4389839..4390276 - 438 Protein_4316 phage integrase SAM-like domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 4369454..4521977 152523


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T95744 NZ_CP026766:4386499-4386602 [Shigella boydii]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT95744 NZ_CP026766:c4386603-4386369 [Shigella boydii]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References