Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 986424..986992 Replicon chromosome
Accession NZ_CP026729
Organism Bifidobacterium catenulatum subsp. kashiwanohense strain APCKJ1

Toxin (Protein)


Gene name relE Uniprot ID A0A087B6G9
Locus tag BKKJ1_RS04540 Protein ID WP_033501734.1
Coordinates 986424..986720 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A6B8LK05
Locus tag BKKJ1_RS04545 Protein ID WP_033501735.1
Coordinates 986723..986992 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BKKJ1_RS04525 983322..984305 + 984 WP_033501732.1 TerC family protein -
BKKJ1_RS04530 984477..985919 + 1443 WP_033501733.1 pyruvate kinase -
BKKJ1_RS04540 986424..986720 - 297 WP_033501734.1 type II toxin-antitoxin system YafQ family toxin Toxin
BKKJ1_RS04545 986723..986992 - 270 WP_033501735.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BKKJ1_RS04550 987299..987505 - 207 WP_065434726.1 hypothetical protein -
BKKJ1_RS04555 987807..989018 + 1212 WP_033501756.1 PLP-dependent aspartate aminotransferase family protein -
BKKJ1_RS04560 989096..989872 + 777 WP_162008475.1 amino acid ABC transporter ATP-binding protein -
BKKJ1_RS04565 989917..990744 + 828 WP_033501737.1 amino acid ABC transporter substrate-binding protein -
BKKJ1_RS04570 990829..991491 + 663 WP_033501738.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-96)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-84)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11419.99 Da        Isoelectric Point: 9.8306

>T95604 WP_033501734.1 NZ_CP026729:c986720-986424 [Bifidobacterium catenulatum subsp. kashiwanohense]
VLQIEYTKAFQRDIKRLKRKHADFSDLKELIRLVAEDTDTAKETLRRRHRAHRLQGGDWDGVIECHVGNAGNWLAIWIKE
DGTAWFLRTGTHAEILGR

Download         Length: 297 bp

>T95604 NZ_CP026729:c986720-986424 [Bifidobacterium catenulatum subsp. kashiwanohense]
GTGCTGCAGATCGAATACACCAAAGCGTTCCAACGGGACATCAAACGACTGAAACGTAAGCATGCCGATTTTTCGGACTT
GAAGGAGCTCATTCGGCTTGTCGCCGAGGATACCGACACAGCAAAGGAGACGTTGCGGCGTCGCCACCGCGCACACAGGC
TACAGGGTGGCGACTGGGACGGCGTTATCGAATGCCATGTCGGCAACGCCGGCAACTGGCTCGCCATATGGATCAAAGAA
GACGGCACCGCCTGGTTCCTGCGAACGGGAACGCATGCCGAAATCCTCGGTAGATGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9897.31 Da        Isoelectric Point: 5.1351

>AT95604 WP_033501735.1 NZ_CP026729:c986992-986723 [Bifidobacterium catenulatum subsp. kashiwanohense]
MTMTSVTVRVDDATKKQATAIVEDLGLDLSSVTRAFYRQIARENRIPLSLSRQSIPAETLDALDEVREKAGKVPPRFKTA
DEMFESLGI

Download         Length: 270 bp

>AT95604 NZ_CP026729:c986992-986723 [Bifidobacterium catenulatum subsp. kashiwanohense]
ATGACCATGACTTCAGTAACGGTCCGCGTGGACGACGCCACGAAAAAACAGGCTACGGCCATCGTGGAGGATCTTGGACT
TGACCTGTCCAGCGTGACCCGCGCGTTCTACCGACAGATCGCCAGGGAGAACCGTATCCCGCTCAGCCTATCGAGGCAAT
CCATTCCGGCTGAGACCCTTGATGCGCTCGACGAGGTGCGCGAGAAGGCAGGGAAGGTTCCCCCACGCTTCAAAACCGCC
GATGAAATGTTCGAATCGCTGGGAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A087B6G9

Antitoxin

Source ID Structure
AlphaFold DB A0A6B8LK05

References