Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 511259..511787 Replicon chromosome
Accession NZ_CP026676
Organism Pseudomonas sp. SWI6

Toxin (Protein)


Gene name relE Uniprot ID A0A2L1HEZ8
Locus tag C4Q28_RS02425 Protein ID WP_027907232.1
Coordinates 511488..511787 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2L1HF13
Locus tag C4Q28_RS02420 Protein ID WP_023382870.1
Coordinates 511259..511498 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4Q28_RS02405 506395..507771 - 1377 WP_104881094.1 HAMP domain-containing protein -
C4Q28_RS02410 507764..508483 - 720 WP_023382872.1 response regulator transcription factor -
C4Q28_RS02415 508640..510919 + 2280 WP_104882327.1 TonB-dependent siderophore receptor -
C4Q28_RS02420 511259..511498 + 240 WP_023382870.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
C4Q28_RS02425 511488..511787 + 300 WP_027907232.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4Q28_RS02430 511909..512765 + 857 WP_104881095.1 IS5 family transposase -
C4Q28_RS02435 513232..513918 + 687 WP_104881096.1 hypothetical protein -
C4Q28_RS26240 514066..514665 - 600 WP_158664616.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 512325..512765 440


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-70)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11497.33 Da        Isoelectric Point: 9.9159

>T95432 WP_027907232.1 NZ_CP026676:511488-511787 [Pseudomonas sp. SWI6]
MTYSLEFDARALKEWQKLGDTVRQQLKKKLASVLLNPRVEANRLHSLPDCYKIKLRSSGYRLVYQVIEQEVVVFVVAVDK
REREQAYLEAAERVVGKTS

Download         Length: 300 bp

>T95432 NZ_CP026676:511488-511787 [Pseudomonas sp. SWI6]
ATGACCTATAGCCTTGAGTTCGATGCGCGAGCGCTAAAGGAATGGCAAAAGCTGGGGGATACGGTCCGGCAGCAACTCAA
GAAAAAACTCGCCTCGGTTTTGCTGAATCCGAGGGTTGAGGCGAACCGGCTGCATAGCTTGCCGGACTGCTACAAGATCA
AGCTGCGCAGTAGCGGCTACCGATTGGTCTACCAGGTGATCGAACAAGAGGTTGTAGTTTTTGTGGTAGCTGTGGATAAG
CGCGAGCGGGAACAGGCTTATCTTGAGGCGGCAGAGCGAGTGGTAGGTAAAACGTCATAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9122.53 Da        Isoelectric Point: 4.6182

>AT95432 WP_023382870.1 NZ_CP026676:511259-511498 [Pseudomonas sp. SWI6]
MASINVRIDDDLKIRAYRELERLGVTPSELMRQALQYVAERGQLPFKPVLMTDEDEALLAIVRERLADPQRVRVSLDDL

Download         Length: 240 bp

>AT95432 NZ_CP026676:511259-511498 [Pseudomonas sp. SWI6]
ATGGCATCCATCAATGTTCGTATCGACGACGATCTCAAAATCCGAGCCTATCGTGAGCTTGAGCGGTTGGGTGTTACGCC
CTCCGAGCTCATGCGCCAAGCCTTGCAGTACGTCGCCGAGCGCGGGCAGTTGCCTTTTAAGCCTGTGCTCATGACTGATG
AAGATGAGGCGCTGCTAGCGATCGTTCGCGAGCGCCTTGCCGACCCTCAGCGAGTGAGGGTTTCGCTGGATGACCTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2L1HEZ8

Antitoxin

Source ID Structure
AlphaFold DB A0A2L1HF13

References