95429

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1430948..1431534 Replicon chromosome
Accession NZ_CP026675
Organism Pseudomonas sp. SWI36

Toxin (Protein)


Gene name PumA Uniprot ID A0A2L1IBQ8
Locus tag C4Q27_RS07050 Protein ID WP_003248568.1
Coordinates 1431241..1431534 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID Q88PM1
Locus tag C4Q27_RS07045 Protein ID WP_003248566.1
Coordinates 1430948..1431244 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4Q27_RS07010 1426324..1426818 - 495 WP_014755382.1 RidA family protein -
C4Q27_RS07015 1426898..1428313 - 1416 WP_041166846.1 FAD-binding oxidoreductase -
C4Q27_RS07025 1428874..1429296 - 423 WP_012051239.1 VOC family protein -
C4Q27_RS07030 1429640..1430287 + 648 WP_104887851.1 serine protease -
C4Q27_RS07040 1430458..1430937 + 480 WP_003248564.1 GNAT family N-acetyltransferase -
C4Q27_RS07045 1430948..1431244 - 297 WP_003248566.1 putative addiction module antidote protein Antitoxin
C4Q27_RS07050 1431241..1431534 - 294 WP_003248568.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4Q27_RS07055 1431758..1432651 + 894 WP_014861462.1 hypothetical protein -
C4Q27_RS07060 1432688..1433455 - 768 WP_104886665.1 phosphonate ABC transporter, permease protein PhnE -
C4Q27_RS07065 1433452..1434279 - 828 WP_064491326.1 ABC transporter permease subunit -
C4Q27_RS07070 1434273..1435082 - 810 WP_064491325.1 phosphonate ABC transporter ATP-binding protein -
C4Q27_RS07075 1435079..1435933 - 855 WP_010952054.1 putative selenate ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-92)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10779.65 Da        Isoelectric Point: 10.9252

>T95429 WP_003248568.1 NZ_CP026675:c1431534-1431241 [Pseudomonas sp. SWI36]
MFLVEQTESFAAWLSSLRDLRARLAIGRRLERAAAGNLGDFKWLGGGIGELRIDVAAGYRIYFTQKGQRLVLLLVGGDKS
TQAADILKARKLLKEMK

Download         Length: 294 bp

>T95429 NZ_CP026675:c1431534-1431241 [Pseudomonas sp. SWI36]
ATGTTTCTCGTTGAACAGACGGAAAGCTTTGCCGCTTGGCTATCGAGCTTGAGAGATTTGAGGGCCAGGCTGGCGATAGG
TCGTAGGCTGGAGCGAGCAGCGGCGGGCAATCTTGGTGACTTCAAGTGGCTTGGAGGCGGTATTGGTGAGCTTCGCATCG
ACGTAGCTGCCGGTTATCGCATCTATTTCACGCAAAAGGGGCAGAGGTTGGTTTTACTGCTGGTCGGCGGCGACAAGTCC
ACCCAGGCCGCCGACATCCTCAAAGCCAGAAAGCTGCTGAAGGAGATGAAATGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10677.32 Da        Isoelectric Point: 6.2205

>AT95429 WP_003248566.1 NZ_CP026675:c1431244-1430948 [Pseudomonas sp. SWI36]
MSEKLIPFDMAALLSSDEAISEYLSQVLSDGDTEEIIRALGHIARARGMTHIATESGLGRESLYKALSPGAKPRFDTVLR
VIRALGVDLLVQPHAMTR

Download         Length: 297 bp

>AT95429 NZ_CP026675:c1431244-1430948 [Pseudomonas sp. SWI36]
ATGAGCGAAAAATTGATCCCGTTTGATATGGCAGCCTTGTTGAGCAGCGATGAGGCAATCAGTGAATACCTTAGCCAGGT
GCTATCAGATGGCGATACCGAGGAAATCATTCGAGCACTTGGCCATATCGCTCGTGCACGGGGCATGACACATATTGCTA
CGGAGAGTGGGCTGGGTAGAGAAAGCCTGTACAAGGCGCTGAGCCCTGGCGCGAAGCCTCGTTTTGACACTGTATTGAGG
GTCATTCGTGCTCTGGGGGTGGACCTTCTCGTTCAGCCACATGCAATGACCCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2L1IBQ8

Antitoxin

Source ID Structure
AlphaFold DB Q88PM1

References