Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicB(antitoxin)
Location 165581..166234 Replicon chromosome
Accession NZ_CP026675
Organism Pseudomonas sp. SWI36

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag C4Q27_RS00965 Protein ID WP_104886297.1
Coordinates 165581..165778 (+) Length 66 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag C4Q27_RS00970 Protein ID WP_104886298.1
Coordinates 165809..166234 (+) Length 142 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4Q27_RS00935 161818..163305 - 1488 WP_104886291.1 terminase -
C4Q27_RS00940 163365..163907 - 543 WP_104886292.1 hypothetical protein -
C4Q27_RS00945 163964..164152 - 189 WP_104886293.1 DUF2158 domain-containing protein -
C4Q27_RS00950 164223..164414 - 192 WP_104886294.1 hypothetical protein -
C4Q27_RS00955 164475..164945 - 471 WP_104886295.1 DUF1311 domain-containing protein -
C4Q27_RS00960 165075..165410 - 336 WP_104886296.1 phage holin, lambda family -
C4Q27_RS00965 165581..165778 + 198 WP_104886297.1 mRNA interferase Toxin
C4Q27_RS00970 165809..166234 + 426 WP_104886298.1 transcriptional regulator Antitoxin
C4Q27_RS00975 166342..167487 - 1146 WP_104886299.1 hypothetical protein -
C4Q27_RS00980 167601..167768 - 168 WP_104886300.1 Com family DNA-binding transcriptional regulator -
C4Q27_RS00985 168072..168662 - 591 WP_104886301.1 hypothetical protein -
C4Q27_RS00990 168778..169383 - 606 WP_104886302.1 recombination protein NinG -
C4Q27_RS29215 169580..169741 - 162 WP_158666112.1 hypothetical protein -
C4Q27_RS01000 169738..170207 - 470 Protein_190 hypothetical protein -
C4Q27_RS01005 170200..170415 - 216 WP_104886304.1 hypothetical protein -
C4Q27_RS01010 170412..171137 - 726 WP_104886305.1 Replication protein P -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 127093..190619 63526


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 66 a.a.        Molecular weight: 7358.57 Da        Isoelectric Point: 10.6925

>T95425 WP_104886297.1 NZ_CP026675:165581-165778 [Pseudomonas sp. SWI36]
MKFSEFRRWLKAQGVAFEAGKEATSKSPPQTAKAIFADHGCKEMPEPTRKAFIKQLGLKEPLRHT

Download         Length: 198 bp

>T95425 NZ_CP026675:165581-165778 [Pseudomonas sp. SWI36]
ATGAAGTTCAGCGAGTTCAGACGATGGTTGAAGGCCCAAGGGGTGGCCTTCGAAGCAGGCAAGGAAGCCACTTCAAAGTC
ACCGCCCCAAACGGCAAAGGCAATCTTCGCGGATCACGGTTGCAAGGAAATGCCAGAACCGACCCGCAAGGCGTTCATTA
AACAACTAGGGCTCAAAGAGCCCCTTCGCCACACCTGA

Antitoxin


Download         Length: 142 a.a.        Molecular weight: 15755.92 Da        Isoelectric Point: 4.6719

>AT95425 WP_104886298.1 NZ_CP026675:165809-166234 [Pseudomonas sp. SWI36]
MYNYAIRFERDDTPGLAVFCRDLPQFHSYGDNEQHALSEAVDGIETTLSIYVDERRSIPAASEPETGELVVHLPAVTVAK
IVLWNEMMARDMRKADLCRLLGLAQTQGDRLVDFRHTSKMEAMETALAALGKQLVVSVEST

Download         Length: 426 bp

>AT95425 NZ_CP026675:165809-166234 [Pseudomonas sp. SWI36]
ATGTACAACTATGCAATCCGCTTTGAGCGCGACGACACACCTGGGCTAGCAGTGTTTTGTCGCGACCTGCCGCAGTTTCA
CAGCTACGGCGATAACGAGCAACACGCGCTAAGCGAAGCGGTGGATGGTATCGAGACGACCCTGTCGATATATGTCGATG
AGCGTCGCTCGATCCCCGCTGCGTCCGAACCTGAGACTGGCGAGTTGGTTGTCCACTTGCCTGCGGTGACCGTGGCGAAG
ATCGTGCTGTGGAACGAAATGATGGCCCGCGATATGCGCAAGGCCGATCTGTGCCGCCTGCTTGGCTTGGCGCAGACCCA
AGGAGATCGTCTTGTCGACTTCCGGCACACTTCGAAGATGGAGGCAATGGAGACGGCGCTAGCCGCGCTCGGCAAACAAC
TGGTGGTGTCTGTCGAGTCGACTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References