Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) hicAB/HicA(toxin)
Location 1387861..1388453 Replicon chromosome
Accession NZ_CP026656
Organism Aliarcobacter cryaerophilus strain M830MA

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag C2860_RS07250 Protein ID WP_115588473.1
Coordinates 1387861..1388109 (+) Length 83 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag C2860_RS07255 Protein ID WP_148571363.1
Coordinates 1388109..1388453 (+) Length 115 a.a.

Genomic Context


C2860_RS07245C2860_RS07250C2860_RS07255C2860_RS07230C2860_RS07235C2860_RS07240C2860_RS07260C2860_RS07265
Location: 1386656..1387816 (1161 bp)
Type: Others
Protein ID: WP_148571361.1
Location: 1387861..1388109 (249 bp)
Type: Toxin
Protein ID: WP_115588473.1
Location: 1388109..1388453 (345 bp)
Type: Antitoxin
Protein ID: WP_148571363.1
Location: 1383928..1384344 (417 bp)
Type: Others
Protein ID: WP_148571355.1
Location: 1384354..1385475 (1122 bp)
Type: Others
Protein ID: WP_148571357.1
Location: 1385566..1386468 (903 bp)
Type: Others
Protein ID: WP_236772668.1
Location: 1388544..1389746 (1203 bp)
Type: Others
Protein ID: WP_252970662.1
Location: 1389819..1392824 (3006 bp)
Type: Others
Protein ID: WP_148571883.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
C2860_RS072301383928..1384344-417WP_148571355.1cyclophilin-like fold protein-
C2860_RS072351384354..1385475-1122WP_148571357.1alpha/beta hydrolase-
C2860_RS072401385566..1386468-903WP_236772668.1AraC family transcriptional regulator-
C2860_RS072451386656..1387816+1161WP_148571361.1MalY/PatB family protein-
C2860_RS072501387861..1388109+249WP_115588473.1type II toxin-antitoxin system HicA family toxinToxin
C2860_RS072551388109..1388453+345WP_148571363.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
C2860_RS072601388544..1389746-1203WP_252970662.1IS256 family transposase-
C2860_RS072651389819..1392824-3006WP_148571883.1DEAD/DEAH box helicase family protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-79)

Antitoxin

(55-104)


Sequences


Toxin        


Download         Length: 83 a.a.        Molecular weight: 9508.43 Da        Isoelectric Point: 10.4132

>T95399 WP_115588473.1 NZ_CP026656:1387861-1388109 [Aliarcobacter cryaerophilus]
MSKKDKLLLKFLENPPKKDLTFKELNTLLISLGFIKIEGAGSAVKFYNKDKDLLINLHKPHPSDILKVYLIKQIQNKLKE
FL

Download         Length: 249 bp

>T95399 NZ_CP026656:1387861-1388109 [Aliarcobacter cryaerophilus]
ATGAGTAAAAAAGATAAACTTTTATTAAAATTTTTAGAAAATCCACCAAAAAAAGATTTAACTTTTAAAGAGTTAAATAC
ATTATTGATATCTTTAGGGTTTATAAAAATTGAAGGTGCTGGTTCTGCTGTTAAATTTTACAATAAAGATAAAGATTTAT
TAATAAATCTACATAAACCGCATCCAAGTGATATTTTAAAAGTTTATCTTATAAAACAGATACAAAACAAACTTAAGGAG
TTTTTATAA

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12987.76 Da        Isoelectric Point: 4.7253

>AT95399 WP_148571363.1 NZ_CP026656:1388109-1388453 [Aliarcobacter cryaerophilus]
MANIIEYNGYIGTIEYSQEDKCFFGKIDMINDLVTFEAQNANELEENFKNAVDEYILTCKELNREPQKAFKGVFNVRTGS
ELHKLAVLNATKIGVSLNTYIKNLIEKDSKLSLN

Download         Length: 345 bp

>AT95399 NZ_CP026656:1388109-1388453 [Aliarcobacter cryaerophilus]
ATGGCAAATATTATTGAGTATAATGGTTATATAGGAACAATTGAGTATTCACAAGAAGATAAATGTTTTTTCGGAAAAAT
AGATATGATAAATGATTTAGTAACATTTGAAGCACAAAATGCAAATGAATTGGAAGAAAATTTTAAAAATGCAGTTGATG
AGTATATCTTGACTTGTAAAGAGCTAAATAGAGAACCACAAAAAGCATTTAAAGGTGTTTTTAATGTACGAACAGGAAGT
GAACTTCACAAACTTGCAGTTTTAAATGCTACAAAAATAGGTGTTTCTCTAAATACCTATATTAAAAATTTGATAGAAAA
AGATAGTAAATTGTCTTTAAATTAG

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References