Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/HicA(toxin) |
Location | 1387861..1388453 | Replicon | chromosome |
Accession | NZ_CP026656 | ||
Organism | Aliarcobacter cryaerophilus strain M830MA |
Toxin (Protein)
Gene name | hicA | Uniprot ID | - |
Locus tag | C2860_RS07250 | Protein ID | WP_115588473.1 |
Coordinates | 1387861..1388109 (+) | Length | 83 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | - |
Locus tag | C2860_RS07255 | Protein ID | WP_148571363.1 |
Coordinates | 1388109..1388453 (+) | Length | 115 a.a. |
Genomic Context
Location: 1386656..1387816 (1161 bp)
Type: Others
Protein ID: WP_148571361.1
Type: Others
Protein ID: WP_148571361.1
Location: 1387861..1388109 (249 bp)
Type: Toxin
Protein ID: WP_115588473.1
Type: Toxin
Protein ID: WP_115588473.1
Location: 1388109..1388453 (345 bp)
Type: Antitoxin
Protein ID: WP_148571363.1
Type: Antitoxin
Protein ID: WP_148571363.1
Location: 1383928..1384344 (417 bp)
Type: Others
Protein ID: WP_148571355.1
Type: Others
Protein ID: WP_148571355.1
Location: 1384354..1385475 (1122 bp)
Type: Others
Protein ID: WP_148571357.1
Type: Others
Protein ID: WP_148571357.1
Location: 1385566..1386468 (903 bp)
Type: Others
Protein ID: WP_236772668.1
Type: Others
Protein ID: WP_236772668.1
Location: 1388544..1389746 (1203 bp)
Type: Others
Protein ID: WP_252970662.1
Type: Others
Protein ID: WP_252970662.1
Location: 1389819..1392824 (3006 bp)
Type: Others
Protein ID: WP_148571883.1
Type: Others
Protein ID: WP_148571883.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C2860_RS07230 | 1383928..1384344 | - | 417 | WP_148571355.1 | cyclophilin-like fold protein | - |
C2860_RS07235 | 1384354..1385475 | - | 1122 | WP_148571357.1 | alpha/beta hydrolase | - |
C2860_RS07240 | 1385566..1386468 | - | 903 | WP_236772668.1 | AraC family transcriptional regulator | - |
C2860_RS07245 | 1386656..1387816 | + | 1161 | WP_148571361.1 | MalY/PatB family protein | - |
C2860_RS07250 | 1387861..1388109 | + | 249 | WP_115588473.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
C2860_RS07255 | 1388109..1388453 | + | 345 | WP_148571363.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
C2860_RS07260 | 1388544..1389746 | - | 1203 | WP_252970662.1 | IS256 family transposase | - |
C2860_RS07265 | 1389819..1392824 | - | 3006 | WP_148571883.1 | DEAD/DEAH box helicase family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 83 a.a. Molecular weight: 9508.43 Da Isoelectric Point: 10.4132
>T95399 WP_115588473.1 NZ_CP026656:1387861-1388109 [Aliarcobacter cryaerophilus]
MSKKDKLLLKFLENPPKKDLTFKELNTLLISLGFIKIEGAGSAVKFYNKDKDLLINLHKPHPSDILKVYLIKQIQNKLKE
FL
MSKKDKLLLKFLENPPKKDLTFKELNTLLISLGFIKIEGAGSAVKFYNKDKDLLINLHKPHPSDILKVYLIKQIQNKLKE
FL
Download Length: 249 bp
>T95399 NZ_CP026656:1387861-1388109 [Aliarcobacter cryaerophilus]
ATGAGTAAAAAAGATAAACTTTTATTAAAATTTTTAGAAAATCCACCAAAAAAAGATTTAACTTTTAAAGAGTTAAATAC
ATTATTGATATCTTTAGGGTTTATAAAAATTGAAGGTGCTGGTTCTGCTGTTAAATTTTACAATAAAGATAAAGATTTAT
TAATAAATCTACATAAACCGCATCCAAGTGATATTTTAAAAGTTTATCTTATAAAACAGATACAAAACAAACTTAAGGAG
TTTTTATAA
ATGAGTAAAAAAGATAAACTTTTATTAAAATTTTTAGAAAATCCACCAAAAAAAGATTTAACTTTTAAAGAGTTAAATAC
ATTATTGATATCTTTAGGGTTTATAAAAATTGAAGGTGCTGGTTCTGCTGTTAAATTTTACAATAAAGATAAAGATTTAT
TAATAAATCTACATAAACCGCATCCAAGTGATATTTTAAAAGTTTATCTTATAAAACAGATACAAAACAAACTTAAGGAG
TTTTTATAA
Antitoxin
Download Length: 115 a.a. Molecular weight: 12987.76 Da Isoelectric Point: 4.7253
>AT95399 WP_148571363.1 NZ_CP026656:1388109-1388453 [Aliarcobacter cryaerophilus]
MANIIEYNGYIGTIEYSQEDKCFFGKIDMINDLVTFEAQNANELEENFKNAVDEYILTCKELNREPQKAFKGVFNVRTGS
ELHKLAVLNATKIGVSLNTYIKNLIEKDSKLSLN
MANIIEYNGYIGTIEYSQEDKCFFGKIDMINDLVTFEAQNANELEENFKNAVDEYILTCKELNREPQKAFKGVFNVRTGS
ELHKLAVLNATKIGVSLNTYIKNLIEKDSKLSLN
Download Length: 345 bp
>AT95399 NZ_CP026656:1388109-1388453 [Aliarcobacter cryaerophilus]
ATGGCAAATATTATTGAGTATAATGGTTATATAGGAACAATTGAGTATTCACAAGAAGATAAATGTTTTTTCGGAAAAAT
AGATATGATAAATGATTTAGTAACATTTGAAGCACAAAATGCAAATGAATTGGAAGAAAATTTTAAAAATGCAGTTGATG
AGTATATCTTGACTTGTAAAGAGCTAAATAGAGAACCACAAAAAGCATTTAAAGGTGTTTTTAATGTACGAACAGGAAGT
GAACTTCACAAACTTGCAGTTTTAAATGCTACAAAAATAGGTGTTTCTCTAAATACCTATATTAAAAATTTGATAGAAAA
AGATAGTAAATTGTCTTTAAATTAG
ATGGCAAATATTATTGAGTATAATGGTTATATAGGAACAATTGAGTATTCACAAGAAGATAAATGTTTTTTCGGAAAAAT
AGATATGATAAATGATTTAGTAACATTTGAAGCACAAAATGCAAATGAATTGGAAGAAAATTTTAAAAATGCAGTTGATG
AGTATATCTTGACTTGTAAAGAGCTAAATAGAGAACCACAAAAAGCATTTAAAGGTGTTTTTAATGTACGAACAGGAAGT
GAACTTCACAAACTTGCAGTTTTAAATGCTACAAAAATAGGTGTTTCTCTAAATACCTATATTAAAAATTTGATAGAAAA
AGATAGTAAATTGTCTTTAAATTAG