Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 2133927..2134440 Replicon chromosome
Accession NZ_CP026616
Organism Acinetobacter sp. SWBY1

Toxin (Protein)


Gene name yoeB Uniprot ID A0A2L2M0A2
Locus tag C3Y93_RS10305 Protein ID WP_000203952.1
Coordinates 2133927..2134190 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID V2U9R0
Locus tag C3Y93_RS10310 Protein ID WP_016658858.1
Coordinates 2134177..2134440 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C3Y93_RS10290 2129988..2131217 + 1230 WP_104852851.1 hypothetical protein -
C3Y93_RS10295 2131683..2131856 - 174 Protein_1990 VF530 family DNA-binding protein -
C3Y93_RS10300 2132326..2133708 - 1383 WP_104852852.1 IS200/IS605 family accessory protein TnpB-related protein -
C3Y93_RS10305 2133927..2134190 - 264 WP_000203952.1 Txe/YoeB family addiction module toxin Toxin
C3Y93_RS10310 2134177..2134440 - 264 WP_016658858.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C3Y93_RS10315 2135083..2138430 + 3348 WP_075167630.1 DEAD/DEAH box helicase -
C3Y93_RS10320 2138496..2138807 - 312 WP_104852853.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10664.10 Da        Isoelectric Point: 8.4894

>T95302 WP_000203952.1 NZ_CP026616:c2134190-2133927 [Acinetobacter sp. SWBY1]
MTSRNVEWTENAWDEYIYWQTQDKKILKRINTLIRECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
IQCRFHY

Download         Length: 264 bp

>T95302 NZ_CP026616:c2134190-2133927 [Acinetobacter sp. SWBY1]
ATGACGAGTCGTAATGTCGAATGGACTGAAAATGCCTGGGATGAATATATCTATTGGCAAACACAGGATAAAAAGATACT
CAAACGTATCAATACCTTAATCAGAGAATGTCAAAGAACACCCTTTGAAGGAACTGGAAAACCAGAACCTTTAAAAGCAA
ATCTTTCAGGATTCTGGAGCCGTAGAATTGATGAGAAGCATAGATTAGTTTATGAAGTGACGGATGAACGAATTTCCATT
ATTCAATGTCGGTTCCATTACTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9826.02 Da        Isoelectric Point: 5.0604

>AT95302 WP_016658858.1 NZ_CP026616:c2134440-2134177 [Acinetobacter sp. SWBY1]
MHVFTYTDARNNLKSVLDKVIDDADVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNTTRLNESIAQLRAGKTKQRE
LIIDDES

Download         Length: 264 bp

>AT95302 NZ_CP026616:c2134440-2134177 [Acinetobacter sp. SWBY1]
ATGCATGTATTTACATATACAGACGCACGTAACAACTTAAAATCTGTTTTAGATAAAGTTATTGATGATGCAGATGTCGC
TTTCATTACAAGAAAAGAAGGCGGTCATGCTGTAGTAATGGGACAAGATCATTACGACAGTTTAATGGAAACGTTGTATC
TCCTTTCATCTCCAAATAATACCACTCGTTTAAACGAATCAATTGCTCAATTACGCGCAGGTAAAACCAAACAAAGAGAG
TTGATTATAGATGACGAGTCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2L2M0A2

Antitoxin

Source ID Structure
AlphaFold DB V2U9R0

References