Detailed information of TA system TA095298

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 1091798..1092326
• Replicon: chromosome
• Accession: NZ_CP026616
• Organism: Acinetobacter sp. SWBY1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: N9CJV8
• Locus tag: C3Y93_RS05265
• Protein ID: WP_004970510.1
• Coordinates: 1092033..1092326 (+)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C3Y93_RS05260
• Protein ID: WP_104852301.1
• Coordinates: 1091798..1092043 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C3Y93_RS05235	1086879..1087307	-	429	WP_104852297.1	YraN family protein	-
C3Y93_RS05240	1087511..1088353	+	843	WP_104852298.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
C3Y93_RS05245	1088545..1088793	-	249	WP_004972644.1	hypothetical protein	-
C3Y93_RS05250	1088970..1090220	-	1251	WP_104852299.1	FAD-dependent monooxygenase	-
C3Y93_RS05255	1090217..1091425	-	1209	WP_104852300.1	2-octaprenyl-6-methoxyphenyl hydroxylase	-
C3Y93_RS05260	1091798..1092043	+	246	WP_104852301.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
C3Y93_RS05265	1092033..1092326	+	294	WP_004970510.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C3Y93_RS05270	1092406..1093740	-	1335	WP_104852302.1	Xaa-Pro aminopeptidase	-
C3Y93_RS05275	1093834..1094472	-	639	WP_004970514.1	UPF0149 family protein	-
C3Y93_RS05280	1094537..1095088	+	552	WP_104852303.1	hypothetical protein	-
C3Y93_RS05285	1095090..1095374	+	285	WP_004970518.1	cell division protein ZapA	-
C3Y93_RS05295	1095715..1096116	-	402	WP_004970519.1	helix-turn-helix domain-containing protein	-
C3Y93_RS05300	1096118..1096408	-	291	WP_019836372.1	type II toxin-antitoxin system HigB family toxin	-
C3Y93_RS05305	1096480..1096974	-	495	WP_004970523.1	flavin reductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (8-85)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-74)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 11279.44 Da
• Isoelectric Point: 10.3743

>T95298 WP_004970510.1 NZ_CP026616:1092033-1092326 [Acinetobacter sp. SWBY1]
MTYNLLRHKDFTAEWEKLPSAIRDQFKKKLAKVIEQPHIPKNMLKGDLAGCYKIKLLKAGVRLIYQVKDDQVVILLITVG
KRADNIVYDEAKKRIKD

Nucleotide

• Length: 294 bp

>T95298 NZ_CP026616:1092033-1092326 [Acinetobacter sp. SWBY1]
ATGACTTATAATCTTTTACGTCACAAGGACTTCACTGCAGAATGGGAAAAGCTTCCGAGTGCTATCCGCGACCAATTCAA
GAAAAAATTAGCCAAAGTCATTGAGCAGCCACATATTCCAAAGAACATGCTTAAAGGTGATCTTGCTGGCTGCTATAAAA
TCAAATTATTAAAAGCGGGTGTCCGACTTATTTATCAGGTCAAAGATGATCAGGTCGTTATTTTGCTCATTACCGTTGGA
AAGCGTGCTGATAACATTGTTTATGATGAAGCAAAAAAGCGGATCAAAGACTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9247.60 Da
• Isoelectric Point: 4.3885

>AT95298 WP_104852301.1 NZ_CP026616:1091798-1092043 [Acinetobacter sp. SWBY1]
MATVNFRVDEALKEKSYSILKEQGISPTDFFTNILEYVATTGKLPVHKALLSEEDAELLALVRKRMNDPKEMFEEVTLDD
L

Nucleotide

• Length: 246 bp

>AT95298 NZ_CP026616:1091798-1092043 [Acinetobacter sp. SWBY1]
ATGGCTACTGTTAATTTCAGGGTCGATGAAGCCCTTAAAGAAAAATCTTATTCAATCCTTAAAGAACAAGGTATCTCACC
TACCGATTTCTTTACCAATATTCTTGAATATGTGGCAACGACTGGAAAGCTTCCAGTACACAAAGCGTTGCTTTCAGAAG
AAGATGCTGAACTATTGGCACTTGTCCGTAAACGCATGAATGATCCTAAAGAGATGTTCGAGGAAGTCACATTAGATGAC
TTATAA

Structures

Toxin

• AlphaFold DB: N9CJV8