Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 120464..122022 Replicon plasmid unnamed1
Accession NZ_CP026605
Organism Catenovulum sp. CCB-QB4

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag C2869_RS22100 Protein ID WP_108605234.1
Coordinates 120706..122022 (+) Length 439 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag C2869_RS22095 Protein ID WP_108605233.1
Coordinates 120464..120712 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2869_RS22085 116754..119018 + 2265 WP_108605231.1 carbohydrate binding family 9 domain-containing protein -
C2869_RS22090 119031..120044 + 1014 WP_108605232.1 extracellular solute-binding protein -
C2869_RS22095 120464..120712 + 249 WP_108605233.1 type II toxin-antitoxin system antitoxin HipB Antitoxin
C2869_RS22100 120706..122022 + 1317 WP_108605234.1 type II toxin-antitoxin system HipA family toxin Toxin
C2869_RS22720 122612..125488 - 2877 WP_199915706.1 hypothetical protein -
C2869_RS22110 125728..126636 - 909 WP_159084286.1 diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..208085 208085


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(150-401)

Antitoxin

Cro/C1-type helix-turn-helix domain

(13-55)


Sequences

Toxin        


Download         Length: 439 a.a.        Molecular weight: 49451.81 Da        Isoelectric Point: 7.4342

>T95252 WP_108605234.1 NZ_CP026605:120706-122022 [Catenovulum sp. CCB-QB4]
MVILNVFMNGFLVGELKKSRDGGHSFTYSQDWLDTRGSRPISLSMPLRKAPYMGDIVYNYFDNLLPDLRDIRERIVTRYN
AESTQVFDLLSVIGRDCVGALQLMPNGNSNFDHKVIKYKSLTNEEVSAILTGYQSNIPLGMLDPENDFRISIAGAQEKTA
LLRLDNQQWARPEGTTPTTHIFKLPIGAIQSHSHTIDLSDSVENEYLCLKIMAGFGIEVPECEIFEHKGVKALVVERFDR
KRSSDKTWIMRLPQEDFCQVNAVSPSKKYESDGGPGIKEIMAFLLSSAESKKDRRDFMKTQVLFWLLGATDGHAKNFSVY
LMPNNAYKLTPIYDVLSAYPACGGCGLNKRKLKLAMALKGKNGKKYDIFTIHKQHFITTAKHVGFNTEEMNEVIDEIAQN
YVCVLEQVEAALPTDFPERITRPIIDNFVKLANSRLAV

Download         Length: 1317 bp

>T95252 NZ_CP026605:120706-122022 [Catenovulum sp. CCB-QB4]
ATGGTGATTTTAAATGTTTTCATGAATGGTTTTTTAGTCGGTGAGCTTAAAAAGAGCCGCGATGGTGGGCATAGTTTTAC
CTACAGTCAAGATTGGTTAGATACCAGAGGTAGTCGCCCTATCTCGCTTTCTATGCCACTACGTAAAGCACCGTATATGG
GGGACATTGTTTATAATTATTTCGATAACCTACTCCCAGATTTAAGAGATATACGAGAGAGGATCGTTACTCGTTACAAT
GCCGAATCAACACAAGTTTTTGACTTATTGAGTGTGATTGGTCGGGACTGTGTAGGTGCTTTGCAGCTAATGCCAAATGG
AAACAGTAACTTCGATCACAAAGTCATCAAATACAAGTCTCTGACGAATGAAGAAGTATCAGCAATACTGACTGGATATC
AAAGTAATATACCACTGGGCATGCTAGATCCAGAAAATGATTTCAGAATATCAATTGCGGGGGCACAAGAGAAAACAGCA
TTACTCAGATTAGATAATCAACAGTGGGCTCGACCTGAAGGTACGACTCCAACAACTCATATTTTTAAACTACCTATTGG
AGCTATTCAAAGCCATTCTCACACAATTGATTTAAGTGACAGTGTAGAAAATGAATACTTATGCTTAAAAATAATGGCTG
GGTTTGGTATTGAAGTACCTGAATGCGAAATATTTGAGCACAAAGGTGTGAAAGCGCTTGTTGTTGAACGCTTTGACAGA
AAAAGATCATCAGATAAAACTTGGATTATGCGCTTGCCACAAGAAGACTTTTGCCAAGTAAACGCTGTTTCACCGTCCAA
AAAATATGAGAGTGATGGTGGGCCCGGAATAAAAGAAATTATGGCATTTTTACTTAGTTCAGCAGAATCTAAGAAAGACC
GTCGAGATTTCATGAAAACACAAGTGTTATTCTGGTTGTTGGGCGCTACAGACGGTCATGCGAAAAACTTTTCTGTGTAC
TTGATGCCAAATAATGCTTACAAACTCACTCCTATCTATGACGTATTGTCAGCTTACCCCGCCTGTGGTGGATGTGGTCT
AAACAAAAGGAAATTAAAGTTAGCCATGGCCTTAAAAGGAAAAAATGGTAAAAAATACGATATATTTACAATACACAAGC
AGCACTTCATAACAACCGCAAAACATGTGGGTTTCAATACCGAAGAAATGAATGAAGTTATTGATGAGATAGCACAGAAT
TATGTGTGCGTTTTAGAGCAAGTTGAAGCTGCTCTTCCAACTGACTTTCCAGAAAGAATAACACGTCCAATCATCGACAA
CTTTGTCAAATTAGCGAATTCAAGACTGGCGGTTTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9423.55 Da        Isoelectric Point: 4.7557

>AT95252 WP_108605233.1 NZ_CP026605:120464-120712 [Catenovulum sp. CCB-QB4]
MIIYSAKQLSAYLRDERKGQSLTQQEVAKQVGIKQNTVSNFENNPDDCTVKTLFKLLSSLELELNVSPKNTDKSTQEWSE
EW

Download         Length: 249 bp

>AT95252 NZ_CP026605:120464-120712 [Catenovulum sp. CCB-QB4]
ATGATCATATATTCTGCCAAACAATTAAGTGCTTATTTGCGTGATGAAAGAAAAGGACAATCGTTAACTCAACAAGAAGT
CGCGAAACAGGTCGGTATAAAGCAAAACACCGTTTCAAACTTTGAGAACAATCCGGATGATTGTACCGTTAAGACGCTGT
TCAAACTGTTGTCATCCTTAGAGCTCGAGCTTAATGTTTCTCCCAAAAACACAGATAAATCTACCCAAGAGTGGTCTGAG
GAATGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References