Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 2346185..2346747 Replicon chromosome
Accession NZ_CP026604
Organism Catenovulum sp. CCB-QB4

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag C2869_RS08120 Protein ID WP_108602458.1
Coordinates 2346185..2346502 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag C2869_RS08125 Protein ID WP_108602459.1
Coordinates 2346502..2346747 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2869_RS08095 2341696..2343207 - 1512 WP_108602453.1 MFS transporter -
C2869_RS08100 2343660..2344358 - 699 WP_108602454.1 M48 family metallopeptidase -
C2869_RS08105 2344791..2345219 + 429 WP_108602455.1 hypothetical protein -
C2869_RS08110 2345289..2345798 + 510 WP_108602456.1 hypothetical protein -
C2869_RS08120 2346185..2346502 - 318 WP_108602458.1 CcdB family protein Toxin
C2869_RS08125 2346502..2346747 - 246 WP_108602459.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
C2869_RS08130 2346929..2348836 - 1908 WP_108602460.1 PhoX family phosphatase -
C2869_RS08135 2348906..2350855 - 1950 WP_159084096.1 phytase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(3-104)

Antitoxin

Post-segregation antitoxin CcdA

(11-81)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11748.55 Da        Isoelectric Point: 4.4205

>T95250 WP_108602458.1 NZ_CP026604:c2346502-2346185 [Catenovulum sp. CCB-QB4]
MPQFSLYKNKDKATTRAYPYFVDVQSDLLSNLDTRIVIPLTPLELLEGAAPSHLCPIIHLEEGDFVILTQQATSVPTKIL
KEEVNDLSAFRNEIIAALDFLFTGI

Download         Length: 318 bp

>T95250 NZ_CP026604:c2346502-2346185 [Catenovulum sp. CCB-QB4]
ATGCCGCAATTTTCACTCTATAAGAACAAAGATAAGGCTACAACGAGAGCTTACCCTTATTTTGTCGATGTTCAATCTGA
TCTTCTGAGTAATTTGGATACAAGAATTGTTATTCCATTGACGCCATTGGAACTTCTTGAAGGGGCAGCCCCAAGCCATT
TGTGCCCAATCATTCACCTTGAAGAGGGTGACTTTGTTATTCTCACTCAACAGGCCACTAGTGTTCCAACTAAGATACTA
AAGGAAGAAGTTAATGACTTGAGTGCTTTTCGAAATGAGATTATCGCAGCACTCGACTTTTTATTTACGGGTATATAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9286.53 Da        Isoelectric Point: 9.7908

>AT95250 WP_108602459.1 NZ_CP026604:c2346747-2346502 [Catenovulum sp. CCB-QB4]
MRNVRSTQPAKKATNLSLNSELLAEAKRLNINLSATMEKALAREVKAKLRDEWINQNTEAVESCNKFTEEHGLFSDSYRK
F

Download         Length: 246 bp

>AT95250 NZ_CP026604:c2346747-2346502 [Catenovulum sp. CCB-QB4]
ATGAGAAATGTACGTTCTACACAACCCGCTAAGAAAGCAACAAACCTTAGCCTAAACAGTGAACTATTGGCTGAAGCGAA
AAGGTTAAACATAAACTTATCTGCAACGATGGAAAAAGCGCTAGCGAGAGAAGTTAAGGCTAAGTTACGTGATGAGTGGA
TTAACCAAAATACTGAAGCAGTTGAATCTTGCAATAAGTTTACTGAAGAGCATGGCTTATTCTCAGATTCTTATAGGAAG
TTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References