Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 2157394..2157865 Replicon chromosome
Accession NZ_CP026604
Organism Catenovulum sp. CCB-QB4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C2869_RS07435 Protein ID WP_108602343.1
Coordinates 2157590..2157865 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag C2869_RS07430 Protein ID WP_108602342.1
Coordinates 2157394..2157606 (+) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2869_RS07400 2153783..2154118 - 336 WP_108602336.1 IS66 family insertion sequence element accessory protein TnpB -
C2869_RS07405 2154115..2154414 - 300 WP_108602337.1 IS66 family insertion sequence hypothetical protein -
C2869_RS07410 2154600..2155178 + 579 WP_108602338.1 hypothetical protein -
C2869_RS07415 2155196..2155681 + 486 WP_159084086.1 hypothetical protein -
C2869_RS07420 2156035..2156952 - 918 WP_108602340.1 DDE-type integrase/transposase/recombinase -
C2869_RS07425 2157049..2157321 + 273 WP_108602341.1 hypothetical protein -
C2869_RS07430 2157394..2157606 + 213 WP_108602342.1 ribbon-helix-helix protein, CopG family Antitoxin
C2869_RS07435 2157590..2157865 + 276 WP_108602343.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C2869_RS07440 2158045..2158377 + 333 WP_108602344.1 hypothetical protein -
C2869_RS07445 2158581..2159507 - 927 WP_108602345.1 DDE-type integrase/transposase/recombinase -
C2869_RS07450 2159878..2161239 + 1362 WP_108602346.1 AAA family ATPase -
C2869_RS07455 2161322..2161819 - 498 WP_108602347.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10930.81 Da        Isoelectric Point: 10.4678

>T95249 WP_108602343.1 NZ_CP026604:2157590-2157865 [Catenovulum sp. CCB-QB4]
MAWKIEWDDHALKDLKKLDKQTQKDIVKYLKTRISTADSPRQFGKSLVGDKIGLWRYRVKDYRIICKIEDDRLVVVVLRT
SHRKNVYRLDI

Download         Length: 276 bp

>T95249 NZ_CP026604:2157590-2157865 [Catenovulum sp. CCB-QB4]
TTGGCTTGGAAGATTGAATGGGATGACCACGCCCTAAAAGACTTAAAAAAATTAGACAAACAAACGCAAAAAGACATTGT
TAAATATCTTAAAACACGAATATCGACAGCCGATTCACCAAGGCAATTTGGCAAATCCTTGGTAGGAGACAAGATCGGCT
TGTGGCGTTATAGAGTTAAAGACTATCGCATCATTTGCAAAATAGAGGACGATAGATTAGTGGTTGTTGTATTGAGGACT
AGCCATAGAAAAAATGTATACAGGTTAGATATTTAA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 8273.38 Da        Isoelectric Point: 4.3575

>AT95249 WP_108602342.1 NZ_CP026604:2157394-2157606 [Catenovulum sp. CCB-QB4]
MLSLRLPVEIEDRLSNLAQTTGRTKTYYAKEAILRYLDEMEDVYIALDRLEKPGKRWTQEEVEQQLGLED

Download         Length: 213 bp

>AT95249 NZ_CP026604:2157394-2157606 [Catenovulum sp. CCB-QB4]
ATGTTATCGTTACGTCTACCTGTAGAAATAGAAGATCGATTATCTAATTTGGCGCAAACAACTGGGCGTACCAAAACTTA
CTATGCCAAAGAAGCTATATTAAGATATTTGGATGAAATGGAAGATGTGTATATTGCCCTAGATAGATTAGAAAAACCAG
GAAAACGCTGGACACAAGAAGAAGTGGAGCAGCAACTTGGCTTGGAAGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References