Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 1973922..1974467 Replicon chromosome
Accession NZ_CP026604
Organism Catenovulum sp. CCB-QB4

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag C2869_RS06970 Protein ID WP_108602263.1
Coordinates 1973922..1974218 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag C2869_RS06975 Protein ID WP_108602264.1
Coordinates 1974225..1974467 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2869_RS06945 1969485..1970567 + 1083 WP_108602259.1 L-rhamnose/proton symporter RhaT -
C2869_RS06950 1970769..1972175 + 1407 WP_108602260.1 L-fucose/L-arabinose isomerase family protein -
C2869_RS06955 1972478..1973050 + 573 WP_108602261.1 hypothetical protein -
C2869_RS06960 1973074..1973376 + 303 WP_108602262.1 hypothetical protein -
C2869_RS22580 1973377..1973799 + 423 WP_199915634.1 protein-export chaperone SecB -
C2869_RS06970 1973922..1974218 - 297 WP_108602263.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C2869_RS06975 1974225..1974467 - 243 WP_108602264.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C2869_RS06980 1974944..1976443 + 1500 WP_108602265.1 BNR-4 repeat-containing protein -
C2869_RS06985 1976589..1977455 + 867 WP_108602266.1 DUF1961 family protein -
C2869_RS06990 1977993..1979132 - 1140 WP_108602267.1 IS110 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-49)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11254.06 Da        Isoelectric Point: 9.6430

>T95248 WP_108602263.1 NZ_CP026604:c1974218-1973922 [Catenovulum sp. CCB-QB4]
MQKNKYKLSKLAQAHLRKIKSYTVSNLSETQWRSYKDTLLIGFQMLADNPALGRCCDDIYPNGFYFPVGKHIAYFTKEDG
FILIVAVLGQTQLPQNHL

Download         Length: 297 bp

>T95248 NZ_CP026604:c1974218-1973922 [Catenovulum sp. CCB-QB4]
ATGCAAAAGAATAAATACAAACTGAGTAAATTAGCTCAGGCTCATTTACGAAAAATCAAAAGCTATACCGTCAGTAATTT
ATCAGAAACACAATGGCGAAGCTACAAAGATACGCTACTGATTGGATTTCAAATGCTTGCAGATAACCCAGCACTTGGTC
GCTGTTGCGACGATATTTACCCAAACGGTTTTTATTTCCCTGTCGGCAAGCACATTGCTTATTTTACAAAAGAAGACGGC
TTTATTTTAATAGTGGCTGTACTCGGTCAAACACAACTTCCACAAAATCACTTGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8969.19 Da        Isoelectric Point: 4.7914

>AT95248 WP_108602264.1 NZ_CP026604:c1974467-1974225 [Catenovulum sp. CCB-QB4]
MHTLTANDAKRNFGELLLSAQREPIKISKNNKDAVVVMSIKDFEELEAMKADYIKHCFESAKQDLAQGNVVDGEDFLNAL

Download         Length: 243 bp

>AT95248 NZ_CP026604:c1974467-1974225 [Catenovulum sp. CCB-QB4]
ATGCACACATTAACGGCAAATGATGCAAAACGTAATTTTGGCGAATTACTACTCAGTGCTCAACGTGAACCAATAAAGAT
TAGCAAAAACAACAAAGACGCGGTTGTTGTAATGTCTATTAAGGACTTTGAAGAATTAGAGGCAATGAAAGCTGACTACA
TTAAACATTGTTTCGAATCCGCTAAACAAGACCTAGCACAAGGTAATGTGGTTGATGGTGAAGACTTTTTAAACGCCTTA
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References