Detailed information of TA system TA095247

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 1295314..1295856
• Replicon: chromosome
• Accession: NZ_CP026604
• Organism: Catenovulum sp. CCB-QB4

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C2869_RS04555
• Protein ID: WP_108601827.1
• Coordinates: 1295584..1295856 (+)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C2869_RS04550
• Protein ID: WP_108601826.1
• Coordinates: 1295314..1295577 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C2869_RS04535	1290371..1291267	+	897	Protein_887	discoidin domain-containing protein	-
C2869_RS04540	1292095..1292997	-	903	WP_108601824.1	hypothetical protein	-
C2869_RS04545	1293126..1294976	-	1851	WP_108601825.1	DUF5060 domain-containing protein	-
C2869_RS04550	1295314..1295577	+	264	WP_108601826.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
C2869_RS04555	1295584..1295856	+	273	WP_108601827.1	type II toxin-antitoxin system YafQ family toxin	Toxin
C2869_RS04560	1296447..1297430	+	984	WP_108601828.1	family 16 glycosylhydrolase	-
C2869_RS04565	1297805..1300108	+	2304	WP_108601829.1	CRTAC1 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (1-89)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (3-83)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10363.97 Da
• Isoelectric Point: 9.3810

>T95247 WP_108601827.1 NZ_CP026604:1295584-1295856 [Catenovulum sp. CCB-QB4]
MYSLEYSSQFKKDFKKITKLAIPDVIEVGHVITQLQSGQQLAVKYVDHALSGNWANYRDCHVKPDLVLIYKIENNTLKLA
RIGSHSELFR

Nucleotide

• Length: 273 bp

>T95247 NZ_CP026604:1295584-1295856 [Catenovulum sp. CCB-QB4]
ATGTATAGCTTAGAATACTCTAGCCAATTTAAGAAAGACTTTAAAAAGATAACAAAACTAGCGATACCAGATGTGATAGA
AGTTGGTCATGTAATTACGCAATTACAAAGTGGCCAACAGCTCGCAGTAAAATATGTAGACCACGCCTTGTCAGGTAACT
GGGCTAATTATAGAGACTGTCACGTTAAACCAGATTTAGTTTTGATTTACAAAATAGAAAACAACACTTTGAAACTTGCT
CGAATAGGTTCACATAGTGAGTTGTTCCGTTAA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9542.90 Da
• Isoelectric Point: 4.7954

>AT95247 WP_108601826.1 NZ_CP026604:1295314-1295577 [Catenovulum sp. CCB-QB4]
MKTEMLSTRIDHDTKLAFTQICDEVGLSPSQAIKLFAKAVINYGGIPFELRSKTPNTETIEAIQELESGAGTKAENVNEL
FKDLGVK

Nucleotide

• Length: 264 bp

>AT95247 NZ_CP026604:1295314-1295577 [Catenovulum sp. CCB-QB4]
ATGAAAACTGAAATGCTGAGCACTCGCATCGATCATGACACTAAGTTAGCTTTTACACAAATATGTGATGAGGTGGGTTT
AAGTCCTTCTCAAGCGATAAAGTTATTTGCTAAGGCGGTAATAAATTATGGTGGTATTCCTTTTGAATTGCGTTCAAAGA
CACCTAACACAGAAACCATTGAAGCAATACAGGAGCTGGAGAGTGGAGCTGGTACAAAAGCAGAAAATGTAAACGAGCTT
TTTAAAGATCTCGGAGTCAAATAA