Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 342947..343746 Replicon chromosome
Accession NZ_CP026604
Organism Catenovulum sp. CCB-QB4

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag C2869_RS01240 Protein ID WP_108601227.1
Coordinates 342947..343480 (-) Length 178 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag C2869_RS01245 Protein ID WP_108601228.1
Coordinates 343477..343746 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2869_RS01220 339047..340102 - 1056 WP_108601223.1 hypothetical protein -
C2869_RS01225 340288..341652 - 1365 WP_108601224.1 AraC family transcriptional regulator -
C2869_RS01230 341981..342280 - 300 WP_108601225.1 type II toxin-antitoxin system RelE/ParE family toxin -
C2869_RS01235 342268..342525 - 258 WP_108601226.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
C2869_RS01240 342947..343480 - 534 WP_108601227.1 GNAT family N-acetyltransferase Toxin
C2869_RS01245 343477..343746 - 270 WP_108601228.1 DUF1778 domain-containing protein Antitoxin
C2869_RS01250 344134..345243 + 1110 WP_108601229.1 transposase -
C2869_RS01260 346386..346664 - 279 WP_108601231.1 hypothetical protein -
C2869_RS01265 346778..347146 - 369 WP_108601232.1 hypothetical protein -
C2869_RS01270 347641..348042 - 402 WP_108601233.1 hypothetical protein -
C2869_RS01275 348372..348641 - 270 WP_108601234.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(97-153)

Antitoxin

Vibrio phage ICP1, Orf50

(5-81)


Sequences

Toxin        


Download         Length: 178 a.a.        Molecular weight: 20058.45 Da        Isoelectric Point: 9.6702

>T95244 WP_108601227.1 NZ_CP026604:c343480-342947 [Catenovulum sp. CCB-QB4]
VSWGKEFVELSKSKHDRNSFDCGEQELNTFIKTLAAKHMQAGISRTMVLPSAQPMLNQKLAICAFYSVAPSSISRETLPA
QLAKKLPRYPIPVFLLAQLAVHKEFHGSGLGKVSLIRALKYLWEVNHHMRAYAIVVDCLTDSAQAFYTKFGFEVLCEHNG
RIRMFLPMKTVEQLFNQ

Download         Length: 534 bp

>T95244 NZ_CP026604:c343480-342947 [Catenovulum sp. CCB-QB4]
GTGAGTTGGGGTAAAGAGTTCGTTGAACTTAGCAAATCAAAGCATGATCGCAACTCATTTGATTGTGGTGAGCAAGAGTT
AAACACGTTTATCAAAACTCTAGCTGCAAAGCACATGCAAGCGGGCATTAGCCGAACAATGGTTTTACCTAGTGCTCAAC
CAATGCTAAATCAAAAACTCGCTATTTGTGCATTTTACAGTGTTGCACCAAGTTCAATCAGCCGAGAAACATTACCGGCA
CAGTTAGCAAAGAAACTTCCTAGATATCCAATCCCTGTTTTTCTTTTGGCTCAATTAGCAGTGCACAAAGAGTTTCATGG
CTCTGGACTAGGAAAGGTTAGCCTTATTCGTGCCCTGAAATACTTGTGGGAAGTGAATCATCACATGCGGGCATACGCAA
TTGTTGTGGACTGTCTTACAGACTCCGCTCAAGCTTTTTATACGAAGTTTGGCTTTGAAGTATTGTGTGAACATAATGGG
CGCATTCGTATGTTCTTACCAATGAAAACGGTAGAACAGCTTTTCAATCAATAG

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9832.26 Da        Isoelectric Point: 4.4452

>AT95244 WP_108601228.1 NZ_CP026604:c343746-343477 [Catenovulum sp. CCB-QB4]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDATQVIEEHESIMVKDSVFDEFMAACNKAKAPNQALLDAA
KFTDESGIK

Download         Length: 270 bp

>AT95244 NZ_CP026604:c343746-343477 [Catenovulum sp. CCB-QB4]
ATGGCAACGGCACGTTTAGATATCCGCCTTGATGAAGAGATCAAGGCAAAAGCCGAAAAAGCATCTGCTCTACTTGGTTT
AAAAAGTCTTACCGAATATGTTGTGAGACTTATGGACGAAGATGCGACTCAAGTTATTGAAGAGCATGAAAGCATTATGG
TCAAAGACAGTGTTTTTGATGAGTTTATGGCTGCGTGTAATAAAGCGAAAGCTCCGAATCAAGCTTTGCTTGATGCTGCC
AAATTTACAGATGAAAGTGGCATTAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References