Detailed information of TA system TA095243

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 341981..342525
• Replicon: chromosome
• Accession: NZ_CP026604
• Organism: Catenovulum sp. CCB-QB4

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C2869_RS01230
• Protein ID: WP_108601225.1
• Coordinates: 341981..342280 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C2869_RS01235
• Protein ID: WP_108601226.1
• Coordinates: 342268..342525 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C2869_RS01220	339047..340102	-	1056	WP_108601223.1	hypothetical protein	-
C2869_RS01225	340288..341652	-	1365	WP_108601224.1	AraC family transcriptional regulator	-
C2869_RS01230	341981..342280	-	300	WP_108601225.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C2869_RS01235	342268..342525	-	258	WP_108601226.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
C2869_RS01240	342947..343480	-	534	WP_108601227.1	GNAT family N-acetyltransferase	-
C2869_RS01245	343477..343746	-	270	WP_108601228.1	DUF1778 domain-containing protein	-
C2869_RS01250	344134..345243	+	1110	WP_108601229.1	transposase	-
C2869_RS01260	346386..346664	-	279	WP_108601231.1	hypothetical protein	-
C2869_RS01265	346778..347146	-	369	WP_108601232.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-87)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-65)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11638.43 Da
• Isoelectric Point: 8.8818

>T95243 WP_108601225.1 NZ_CP026604:c342280-341981 [Catenovulum sp. CCB-QB4]
MAEVIWTSPALDDLNEIAEYIALSNLSAAKKLTQKIFDKITRLENHPESGKRPKELADLNYREVNVNPCRIFYKVDSDKV
YILNVMRQERDLRRFLLKN

Nucleotide

• Length: 300 bp

>T95243 NZ_CP026604:c342280-341981 [Catenovulum sp. CCB-QB4]
ATGGCTGAAGTAATTTGGACATCACCAGCCCTTGATGATTTAAACGAGATCGCTGAATACATTGCTTTAAGCAACCTATC
TGCTGCAAAGAAGTTGACTCAAAAAATATTTGATAAAATAACTAGATTAGAAAATCATCCGGAGTCGGGTAAAAGGCCAA
AGGAATTGGCGGACTTAAATTACCGTGAAGTAAATGTTAATCCTTGTCGTATCTTTTATAAAGTAGATAGCGACAAAGTT
TATATTTTAAATGTTATGCGTCAAGAACGAGATCTACGTAGGTTTCTTTTAAAGAATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9769.29 Da
• Isoelectric Point: 8.4848

>AT95243 WP_108601226.1 NZ_CP026604:c342525-342268 [Catenovulum sp. CCB-QB4]
MRVELVTTLKRQATKILSDLHKSKEPVLITEHGQPSAYLVDVEDYEFMQQRMAILEGVARGEQAIKYGETFSNQEAKAKM
SKWLK

Nucleotide

• Length: 258 bp

>AT95243 NZ_CP026604:c342525-342268 [Catenovulum sp. CCB-QB4]
ATGAGAGTTGAACTTGTAACAACACTTAAGCGGCAAGCTACTAAAATTCTATCTGACCTACATAAATCAAAAGAACCTGT
ACTAATTACGGAGCATGGTCAACCATCTGCTTACTTAGTTGATGTGGAAGATTATGAGTTTATGCAACAGCGAATGGCAA
TTCTTGAAGGTGTTGCACGCGGTGAGCAAGCAATTAAATATGGTGAAACGTTTTCAAACCAAGAAGCAAAAGCGAAAATG
AGTAAATGGCTGAAGTAA