Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2037158..2037429 Replicon chromosome
Accession NZ_CP026580
Organism Escherichia coli strain WCHEC005237

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2037288..2037391 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2037158..2037429 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4E05_RS12030 2033713..2034375 - 663 WP_000944256.1 exodeoxyribonuclease X -
C4E05_RS12035 2034399..2035055 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C4E05_RS12040 2035157..2035387 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C4E05_RS12045 2035526..2035900 + 375 WP_000168747.1 CopC domain-containing protein YobA -
C4E05_RS12050 2035904..2036776 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
C4E05_RS12055 2036789..2037130 + 342 WP_000976476.1 YebY family protein -
- 2037158..2037429 - 272 - - Antitoxin
- 2037288..2037391 + 104 - - Toxin
C4E05_RS12060 2037526..2038182 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
C4E05_RS12065 2038183..2038374 - 192 WP_000457842.1 YebW family protein -
C4E05_RS12070 2038479..2038715 - 237 WP_001295499.1 DUF1480 family protein -
C4E05_RS12075 2038833..2040272 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T95135 NZ_CP026580:2037288-2037391 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT95135 NZ_CP026580:c2037429-2037158 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References