Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 62277..62799 Replicon plasmid pSE1004839
Accession NZ_CP026570
Organism Salmonella enterica strain MFDS1004839

Toxin (Protein)


Gene name relE Uniprot ID D0QMR1
Locus tag MFDS1004839_RS24325 Protein ID WP_000220561.1
Coordinates 62277..62558 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID G3CAG1
Locus tag MFDS1004839_RS24330 Protein ID WP_000121743.1
Coordinates 62548..62799 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MFDS1004839_RS24275 58260..58805 - 546 WP_000757692.1 hypothetical protein -
MFDS1004839_RS24820 58800..58874 - 75 Protein_76 DNA distortion polypeptide 3 -
MFDS1004839_RS24285 59131..59403 - 273 WP_000167280.1 hypothetical protein -
MFDS1004839_RS24295 59636..59815 - 180 WP_000439079.1 hypothetical protein -
MFDS1004839_RS24300 59857..60186 - 330 WP_000866654.1 hypothetical protein -
MFDS1004839_RS24305 60280..60522 - 243 WP_000008708.1 hypothetical protein -
MFDS1004839_RS24310 60512..60724 - 213 WP_001446884.1 hypothetical protein -
MFDS1004839_RS24315 60790..61338 - 549 WP_001178641.1 hypothetical protein -
MFDS1004839_RS24320 61412..61927 - 516 WP_001025387.1 J domain-containing protein -
MFDS1004839_RS24325 62277..62558 - 282 WP_000220561.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MFDS1004839_RS24330 62548..62799 - 252 WP_000121743.1 plasmid stabilization protein Antitoxin
MFDS1004839_RS24335 63864..64733 + 870 WP_001212191.1 replication initiation protein -
MFDS1004839_RS24340 64738..65589 + 852 WP_000435059.1 replication initiation protein -
MFDS1004839_RS24345 65593..66038 + 446 Protein_88 hypothetical protein -
MFDS1004839_RS24350 66106..66528 + 423 WP_000202950.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..96994 96994


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 13852.62 Da        Isoelectric Point: 5.5500

>T95112 WP_000220561.1 NZ_CP026570:c62558-62277 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFF

Download         Length: 282 bp

>T95112 NZ_CP026570:c62558-62277 [Salmonella enterica]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 12380.85 Da        Isoelectric Point: 5.5500

>AT95112 WP_000121743.1 NZ_CP026570:c62799-62548 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFF

Download         Length: 252 bp

>AT95112 NZ_CP026570:c62799-62548 [Salmonella enterica]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3S5I302

Antitoxin

Source ID Structure
AlphaFold DB A0A3S5I301

References