Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1203889..1204373 Replicon chromosome
Accession NZ_CP026562
Organism Pseudomonas avellanae strain R2leaf

Toxin (Protein)


Gene name relE Uniprot ID A0A2S4ID74
Locus tag BKM03_RS06155 Protein ID WP_005736616.1
Coordinates 1203889..1204107 (-) Length 73 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2S4IDD5
Locus tag BKM03_RS06160 Protein ID WP_005736615.1
Coordinates 1204107..1204373 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BKM03_RS06125 1198962..1199987 - 1026 WP_005736621.1 TRAP transporter substrate-binding protein -
BKM03_RS06130 1200045..1200929 - 885 WP_005736620.1 SMP-30/gluconolactonase/LRE family protein -
BKM03_RS06135 1200986..1201813 - 828 WP_005736619.1 NAD(P)-dependent oxidoreductase -
BKM03_RS06140 1201992..1203260 - 1269 WP_017698468.1 OprD family porin -
BKM03_RS06155 1203889..1204107 - 219 WP_005736616.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BKM03_RS06160 1204107..1204373 - 267 WP_005736615.1 ribbon-helix-helix domain-containing protein Antitoxin
BKM03_RS06165 1204538..1206460 - 1923 WP_017700186.1 methyl-accepting chemotaxis protein -
BKM03_RS06170 1206819..1208699 + 1881 WP_005736612.1 methyl-accepting chemotaxis protein -
BKM03_RS06175 1208828..1209091 - 264 WP_005736610.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-72)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8285.65 Da        Isoelectric Point: 8.5052

>T95104 WP_005736616.1 NZ_CP026562:c1204107-1203889 [Pseudomonas avellanae]
MELMWTSKALSDVARLYDFLAVASQPAAAQTVQKLTAAPIMLLSNPRIGERLEEFEPRDVRKIQIGRYEMRY

Download         Length: 219 bp

>T95104 NZ_CP026562:c1204107-1203889 [Pseudomonas avellanae]
ATGGAGCTGATGTGGACAAGCAAAGCGCTATCTGACGTCGCCCGCCTGTATGATTTTTTAGCGGTAGCAAGCCAACCCGC
TGCCGCCCAGACCGTACAGAAGCTTACAGCGGCGCCGATCATGCTCCTTTCCAACCCCCGGATTGGCGAGCGTCTGGAAG
AGTTTGAGCCCCGGGATGTGCGCAAAATCCAGATAGGCCGCTACGAAATGCGCTACTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9915.20 Da        Isoelectric Point: 5.6158

>AT95104 WP_005736615.1 NZ_CP026562:c1204373-1204107 [Pseudomonas avellanae]
MTTKTRSVTAHIPEQLAEKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGHVIDHQAVQAWADSLST
ATPLPVPR

Download         Length: 267 bp

>AT95104 NZ_CP026562:c1204373-1204107 [Pseudomonas avellanae]
ATGACAACCAAGACCCGATCTGTAACAGCTCACATACCCGAACAATTGGCTGAAAAAGTCGACCTGATGGCAGAGCGACT
CGAACGCTCTAAAAACTGGATCGTCAAACAGGCCTTGTCTGCATGGATAGATCAGGAGGAAGAACGTAGTCGCCTCACTC
GCGAAGCATTAGCCGATGTCGATGCTGGCCATGTGATTGACCATCAGGCTGTTCAGGCCTGGGCTGACAGTTTAAGCACC
GCTACGCCTCTACCGGTTCCGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2S4ID74

Antitoxin

Source ID Structure
AlphaFold DB A0A2S4IDD5

References