Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 30001..30479 Replicon plasmid p2_tig3
Accession NZ_CP026559
Organism Pseudomonas amygdali pv. morsprunorum strain R15244

Toxin (Protein)


Gene name relE Uniprot ID H1ZX33
Locus tag BKM19_RS30005 Protein ID WP_003348565.1
Coordinates 30001..30294 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2S4HLF9
Locus tag BKM19_RS30010 Protein ID WP_003348562.1
Coordinates 30294..30479 (-) Length 62 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BKM19_RS29960 25459..25734 - 276 Protein_30 peptidase S24 -
BKM19_RS29965 25760..26254 - 495 WP_103377105.1 hypothetical protein -
BKM19_RS29970 26344..26574 - 231 WP_057446617.1 hypothetical protein -
BKM19_RS29980 27027..27308 + 282 WP_015062535.1 hypothetical protein -
BKM19_RS29985 27289..28518 + 1230 WP_015062536.1 IS91 family transposase -
BKM19_RS29990 28809..29153 + 345 Protein_35 transposase -
BKM19_RS30000 29358..29885 - 528 WP_057416414.1 hypothetical protein -
BKM19_RS30005 30001..30294 - 294 WP_003348565.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BKM19_RS30010 30294..30479 - 186 WP_003348562.1 hypothetical protein Antitoxin
BKM19_RS30015 30566..30859 - 294 WP_103356847.1 HU family DNA-binding protein -
BKM19_RS30020 31085..32398 - 1314 WP_053479516.1 replication initiation protein -
BKM19_RS30025 32876..33556 + 681 WP_141562502.1 hypothetical protein -
BKM19_RS30030 33678..33959 + 282 WP_015062535.1 hypothetical protein -
BKM19_RS30035 33940..35169 + 1230 WP_015062536.1 IS91 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..168854 168854
- inside IScluster/Tn - - 27289..35169 7880


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11136.84 Da        Isoelectric Point: 6.2150

>T95099 WP_003348565.1 NZ_CP026559:c30294-30001 [Pseudomonas amygdali pv. morsprunorum]
MLPIFWLESADNDLAAIIEYIGSRDIAAAERLWQRLRGIVLPLSEHPYLYAISDRVPGMREIVAHPNYLVFYRVTSTRIE
VVNVVHARQEYPQTGLA

Download         Length: 294 bp

>T95099 NZ_CP026559:c30294-30001 [Pseudomonas amygdali pv. morsprunorum]
ATGCTACCCATTTTCTGGCTAGAATCAGCGGACAACGATTTGGCGGCAATAATCGAATACATAGGTTCACGTGATATAGC
TGCTGCCGAAAGGTTATGGCAGCGCTTGCGTGGCATCGTTCTGCCCCTTTCAGAACATCCTTATCTGTATGCGATAAGTG
ACCGCGTCCCAGGAATGCGCGAGATCGTTGCCCATCCTAACTACCTGGTGTTTTATCGTGTCACCTCAACGCGCATAGAA
GTGGTGAACGTCGTCCACGCACGGCAAGAATATCCCCAAACTGGACTAGCGTAG

Antitoxin


Download         Length: 62 a.a.        Molecular weight: 7134.04 Da        Isoelectric Point: 6.4675

>AT95099 WP_003348562.1 NZ_CP026559:c30479-30294 [Pseudomonas amygdali pv. morsprunorum]
MIDRSPIVSEFETEELEANYTAWLRAKVEASLADSRPAIPHDEVERRMAERLARLRHRRAS

Download         Length: 186 bp

>AT95099 NZ_CP026559:c30479-30294 [Pseudomonas amygdali pv. morsprunorum]
ATGATTGATCGTTCGCCTATCGTTTCGGAGTTTGAAACTGAAGAGCTAGAGGCCAATTACACCGCCTGGCTACGCGCGAA
GGTGGAGGCAAGTCTGGCCGACTCGCGCCCTGCTATCCCGCATGATGAAGTCGAGCGAAGGATGGCAGAGCGGTTGGCAC
GATTGCGCCATCGCCGAGCGTCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A193SFZ9

Antitoxin

Source ID Structure
AlphaFold DB A0A2S4HLF9

References