Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 5849048..5849567 Replicon chromosome
Accession NZ_CP026558
Organism Pseudomonas amygdali pv. morsprunorum strain R15244

Toxin (Protein)


Gene name relE Uniprot ID Q48Q48
Locus tag BKM19_RS28595 Protein ID WP_002551445.1
Coordinates 5849048..5849338 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag BKM19_RS28600 Protein ID WP_002551444.1
Coordinates 5849328..5849567 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BKM19_RS28565 5844472..5845275 - 804 WP_003417182.1 IS21-like element ISPsy20 family helper ATPase IstB -
BKM19_RS28570 5845268..5846767 - 1500 WP_103356851.1 IS21 family transposase -
BKM19_RS28580 5847350..5847772 + 423 WP_005746664.1 DUF1493 family protein -
BKM19_RS28585 5848078..5848815 + 738 WP_060403416.1 hypothetical protein -
BKM19_RS28595 5849048..5849338 - 291 WP_002551445.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BKM19_RS28600 5849328..5849567 - 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BKM19_RS28605 5849731..5850204 - 474 WP_002551443.1 GNAT family N-acetyltransferase -
BKM19_RS28610 5850306..5850854 - 549 WP_044318253.1 GNAT family N-acetyltransferase -
BKM19_RS28615 5851014..5851508 + 495 WP_004667254.1 hypothetical protein -
BKM19_RS28620 5851542..5852816 - 1275 WP_004667253.1 OprD family porin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11316.19 Da        Isoelectric Point: 10.2579

>T95098 WP_002551445.1 NZ_CP026558:c5849338-5849048 [Pseudomonas amygdali pv. morsprunorum]
MTYNLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
REREEVYRKATDRLGR

Download         Length: 291 bp

>T95098 NZ_CP026558:c5849338-5849048 [Pseudomonas amygdali pv. morsprunorum]
ATGACCTATAACCTCGAATTCGATGCGCGGGCTCTAAAGGAATGGCACAAATTAGGAGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCTCCGCGTGTTGAAGCCAATCGTCTGCATGCATTGCCTGACTGCTACAAAATCA
AACTGCGCAGTAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCGGTAGACAAG
CGTGAACGGGAAGAGGTTTATCGCAAGGCGACGGACCGGCTGGGTAGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT95098 WP_002551444.1 NZ_CP026558:c5849567-5849328 [Pseudomonas amygdali pv. morsprunorum]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp

>AT95098 NZ_CP026558:c5849567-5849328 [Pseudomonas amygdali pv. morsprunorum]
ATGGCGTCTATCAACGTTCGTATCGACGACGATCTCAAAGCGCGTGCTTACCTCGAGCTGGAAAAGCTTGGCGTCACCCC
CTCGGAGTTGCTGCGCCAAACCCTGCAGTACGTAGCTGAGCGTGGTCAGCTACCCTTCAAGACGGTTCTGATGACAGAGG
AAGACGAAGCGCTGTTGGCAACTGTGCGCGAGCGCCTTGCAGCTCCGCAGCGGGTCAAGGTTTCACTGGATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G4DBS4

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References