Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 180123..180570 Replicon chromosome
Accession NZ_CP026558
Organism Pseudomonas amygdali pv. morsprunorum strain R15244

Toxin (Protein)


Gene name relE Uniprot ID A0A3M4C5F0
Locus tag BKM19_RS01485 Protein ID WP_003348606.1
Coordinates 180123..180395 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3M4C5H0
Locus tag BKM19_RS01490 Protein ID WP_005730485.1
Coordinates 180385..180570 (-) Length 62 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BKM19_RS01445 175569..175850 - 282 WP_015062535.1 hypothetical protein -
BKM19_RS31430 175932..176075 + 144 Protein_169 transposase -
BKM19_RS01450 176078..176305 + 228 WP_004642455.1 hypothetical protein -
BKM19_RS01455 176381..176956 - 576 WP_060402810.1 recombinase family protein -
BKM19_RS01460 177501..178322 + 822 WP_005735297.1 C58 family peptidase -
BKM19_RS01465 178361..178549 + 189 Protein_173 helix-turn-helix domain-containing protein -
BKM19_RS32050 178553..178765 + 213 Protein_174 DUF4158 domain-containing protein -
BKM19_RS01475 178763..179094 + 332 Protein_175 Tn3 family transposase -
BKM19_RS01480 179199..179912 - 714 WP_053479514.1 UPF0149 family protein -
BKM19_RS01485 180123..180395 - 273 WP_003348606.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BKM19_RS01490 180385..180570 - 186 WP_005730485.1 hypothetical protein Antitoxin
BKM19_RS01495 180621..180899 - 279 WP_053479513.1 hypothetical protein -
BKM19_RS01500 180992..181627 - 636 WP_054068142.1 recombinase family protein -
BKM19_RS01505 181972..182670 + 699 WP_005734862.1 ParA family protein -
BKM19_RS01510 182663..182986 + 324 WP_007253135.1 hypothetical protein -
BKM19_RS01525 183316..184815 + 1500 WP_103356851.1 IS21 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 113913..273504 159591
- flank IS/Tn - - 174359..175567 1208


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10199.67 Da        Isoelectric Point: 5.0749

>T95095 WP_003348606.1 NZ_CP026558:c180395-180123 [Pseudomonas amygdali pv. morsprunorum]
VLVEWLPQALEALEEIAGYLAERNPYAAEQMQATLEATVEALPLHPYIHRPGRVPGTREAVVHPNYLVVYRVGTERISIL
DVLHARQEYP

Download         Length: 273 bp

>T95095 NZ_CP026558:c180395-180123 [Pseudomonas amygdali pv. morsprunorum]
GTGCTAGTTGAGTGGCTTCCACAAGCTTTGGAGGCACTGGAGGAAATCGCCGGCTACCTAGCCGAGCGCAACCCTTATGC
TGCCGAGCAGATGCAGGCCACCCTTGAGGCCACGGTCGAGGCTCTCCCCCTGCACCCTTACATCCACCGTCCCGGCCGTG
TTCCAGGAACGCGCGAAGCGGTTGTGCATCCCAACTACCTGGTTGTCTACCGCGTCGGTACAGAGCGCATCAGCATCTTG
GACGTCCTGCACGCCCGCCAAGAGTACCCCTAG

Antitoxin


Download         Length: 62 a.a.        Molecular weight: 7292.18 Da        Isoelectric Point: 7.2040

>AT95095 WP_005730485.1 NZ_CP026558:c180570-180385 [Pseudomonas amygdali pv. morsprunorum]
MSIQLDPRVSEFETQEQADNYDRWFRQRIEHSLADPRPPVPHDEAMARVRAMIEAKRRRAS

Download         Length: 186 bp

>AT95095 NZ_CP026558:c180570-180385 [Pseudomonas amygdali pv. morsprunorum]
ATGAGCATTCAACTTGACCCTCGCGTCTCGGAGTTCGAGACCCAGGAACAGGCCGACAATTACGACCGTTGGTTTCGCCA
GCGTATCGAGCACAGTTTGGCCGATCCGCGTCCACCCGTGCCGCACGATGAAGCAATGGCTCGCGTCAGAGCAATGATCG
AAGCAAAGCGCCGCCGTGCTAGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3M4C5F0

Antitoxin

Source ID Structure
AlphaFold DB A0A3M4C5H0

References