Detailed information of TA system TA095086

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 123559..124136
• Replicon: plasmid pDCAR1
• Accession: NZ_CP026539
• Organism: Desulfovibrio carbinolicus strain DSM 3852

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: C3Y92_RS20780
• Protein ID: WP_129356138.1
• Coordinates: 123559..123855 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C3Y92_RS20785
• Protein ID: WP_129356140.1
• Coordinates: 123843..124136 (-)
• Length: 98 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C3Y92_RS20775	120979..123276	-	2298	WP_165352190.1	cobalamin-dependent protein	-
C3Y92_RS20780	123559..123855	-	297	WP_129356138.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C3Y92_RS20785	123843..124136	-	294	WP_129356140.1	ribbon-helix-helix protein, CopG family	Antitoxin
C3Y92_RS20790	124429..125103	-	675	WP_129356142.1	phosphocholine cytidylyltransferase family protein	-
C3Y92_RS20795	125100..126326	-	1227	WP_129356144.1	CDP-glycerol glycerophosphotransferase family protein	-
C3Y92_RS20800	126712..127512	+	801	WP_012750659.1	ParA family protein	-
C3Y92_RS20805	127493..128893	+	1401	WP_129356146.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..132673	132673

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-96)

Antitoxin

• Ribbon-helix-helix protein, CopG (10-47)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 10951.83 Da
• Isoelectric Point: 9.3766

>T95086 WP_129356138.1 NZ_CP026539:c123855-123559 [Desulfovibrio carbinolicus]
MPHLKLVWSPAALLGVQRAYRFLAEKDADAARAAVSAIRKYAAILKKFPNAGRPAEDLDPEHRELLIPFGLSGYVLVYEL
HAEMILVLALRHQKEAGY

Nucleotide

• Length: 297 bp

>T95086 NZ_CP026539:c123855-123559 [Desulfovibrio carbinolicus]
ATGCCACATTTGAAGCTGGTGTGGTCGCCTGCCGCGCTCCTGGGCGTGCAGCGGGCCTACCGTTTCCTTGCCGAAAAGGA
CGCCGACGCCGCGCGGGCCGCGGTGTCGGCCATCAGAAAATACGCGGCTATCTTGAAAAAATTTCCCAACGCCGGCCGTC
CGGCCGAGGATTTGGACCCGGAACACCGGGAATTGCTGATTCCCTTCGGCCTGTCCGGGTATGTGCTGGTCTACGAGTTG
CATGCCGAAATGATCCTGGTGTTGGCCCTGCGCCACCAAAAAGAAGCCGGGTACTGA

Antitoxin

Protein

• Length: 98 a.a.
• Molecular weight: 10939.56 Da
• Isoelectric Point: 6.0792

>AT95086 WP_129356140.1 NZ_CP026539:c124136-123843 [Desulfovibrio carbinolicus]
MPTQTQATPTSIKLPVALRERLQQLARMRKRTPHALMLQALETYVAREEQREALRQEALAAHEAFMLTGLHVTAEEADAW
LAELEAGNDVEPPKCHI

Nucleotide

• Length: 294 bp

>AT95086 NZ_CP026539:c124136-123843 [Desulfovibrio carbinolicus]
ATGCCGACGCAGACTCAGGCCACGCCGACGAGCATCAAGCTTCCCGTGGCCTTGCGGGAGCGGTTGCAACAGCTGGCGCG
GATGCGCAAGCGCACGCCGCACGCGCTCATGCTCCAGGCGCTGGAAACGTATGTGGCCAGGGAAGAGCAGCGGGAAGCCT
TGCGCCAGGAAGCCCTGGCCGCCCATGAGGCCTTTATGCTGACCGGTCTGCATGTGACGGCCGAGGAAGCCGACGCCTGG
CTGGCCGAGTTGGAAGCGGGAAACGACGTGGAACCGCCGAAATGCCACATTTGA