Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-ChpS
Location 332675..333264 Replicon chromosome
Accession NZ_CP026538
Organism Desulfovibrio carbinolicus strain DSM 3852

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag C3Y92_RS01425 Protein ID WP_129348795.1
Coordinates 332675..333007 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag C3Y92_RS01430 Protein ID WP_129348797.1
Coordinates 333007..333264 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C3Y92_RS01405 327765..328952 - 1188 WP_129348787.1 GGDEF domain-containing protein -
C3Y92_RS01410 329108..330532 - 1425 WP_129348789.1 adenosylhomocysteinase -
C3Y92_RS01415 330548..331480 - 933 WP_129348791.1 metalloregulator ArsR/SmtB family transcription factor -
C3Y92_RS01420 331555..332547 - 993 WP_129348793.1 hypothetical protein -
C3Y92_RS01425 332675..333007 - 333 WP_129348795.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
C3Y92_RS01430 333007..333264 - 258 WP_129348797.1 antitoxin Antitoxin
C3Y92_RS01435 333491..333871 + 381 WP_129348799.1 response regulator -
C3Y92_RS01440 333935..336754 - 2820 WP_129348801.1 response regulator -
C3Y92_RS01445 336868..337881 - 1014 WP_129348803.1 SPASM domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-105)

Antitoxin

Antitoxin PemI-like

(5-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11323.02 Da        Isoelectric Point: 9.2703

>T95082 WP_129348795.1 NZ_CP026538:c333007-332675 [Desulfovibrio carbinolicus]
MERGDIYLVSLDPTAGHEQQGTRPVLIISPGAFNRLTGTPVVLPITTGGNFARTAGFAVSLEGAGTRTTGVVRCDQPRAL
DVAARGGRKLESVPPGVMAEVLGRVGVIVG

Download         Length: 333 bp

>T95082 NZ_CP026538:c333007-332675 [Desulfovibrio carbinolicus]
ATGGAGCGCGGCGACATTTATCTCGTGTCCCTGGACCCGACGGCCGGCCATGAGCAGCAAGGCACGCGGCCGGTGCTGAT
CATCTCGCCCGGCGCGTTTAATCGCCTCACCGGCACGCCTGTCGTCTTGCCCATCACCACCGGCGGCAATTTCGCCCGCA
CGGCCGGCTTCGCCGTGTCCCTGGAAGGAGCCGGCACGCGGACCACCGGCGTGGTGCGCTGCGACCAGCCCCGCGCCCTG
GATGTGGCGGCGCGCGGCGGCCGGAAGCTGGAGAGCGTGCCGCCGGGCGTCATGGCGGAGGTTTTGGGGAGGGTGGGGGT
GATTGTGGGGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9034.38 Da        Isoelectric Point: 4.4455

>AT95082 WP_129348797.1 NZ_CP026538:c333264-333007 [Desulfovibrio carbinolicus]
MHTTNLRKVGGSVMLAVPPAILELLALQAGSSVGLAVADGRLVIEPIRPPRYTLDELLAQCDASAAVSDEDRQWLDGRPT
GNELL

Download         Length: 258 bp

>AT95082 NZ_CP026538:c333264-333007 [Desulfovibrio carbinolicus]
ATGCACACCACCAATCTGCGCAAAGTCGGGGGATCGGTCATGCTGGCCGTGCCGCCGGCCATCCTCGAACTGCTGGCGTT
GCAGGCCGGCTCCAGCGTCGGGCTGGCCGTGGCCGACGGCCGGCTGGTGATCGAGCCGATCCGGCCGCCGCGCTACACCC
TGGACGAGCTGCTGGCCCAGTGCGACGCCTCGGCCGCCGTCAGCGACGAAGACCGGCAGTGGCTGGACGGCCGGCCGACC
GGCAATGAGCTTTTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References