Detailed information of TA system TA095056

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-RelB
• Location: 492221..492723
• Replicon: chromosome
• Accession: NZ_CP026530
• Organism: Nautilia sp. PV-1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C3L23_RS02740
• Protein ID: WP_127679631.1
• Coordinates: 492466..492723 (+)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: C3L23_RS02735
• Protein ID: WP_127679630.1
• Coordinates: 492221..492466 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C3L23_RS02710	487495..488163	+	669	WP_127679625.1	ABC transporter ATP-binding protein	-
C3L23_RS02715	488150..488935	+	786	WP_127679626.1	hypothetical protein	-
C3L23_RS02720	488932..490050	+	1119	WP_127679627.1	M23 family metallopeptidase	-
C3L23_RS02725	490133..491455	+	1323	WP_127679628.1	transcription termination factor Rho	-
C3L23_RS02730	491448..492185	+	738	WP_127679629.1	glutamate racemase	-
C3L23_RS02735	492221..492466	+	246	WP_127679630.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
C3L23_RS02740	492466..492723	+	258	WP_127679631.1	Txe/YoeB family addiction module toxin	Toxin
C3L23_RS02750	492983..493243	-	261	WP_127679632.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
C3L23_RS02755	493286..493921	-	636	WP_127679633.1	SDR family NAD(P)-dependent oxidoreductase	-
C3L23_RS02760	494151..495068	-	918	WP_127679634.1	radical SAM protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 10375.12 Da
• Isoelectric Point: 8.4644

>T95056 WP_127679631.1 NZ_CP026530:492466-492723 [Nautilia sp. PV-1]
MKIAFTLEGWEDYIYWQKIDKKIVKKINELIKDIKRHPFEGLGKPEALKFDFAGCYSRRINHEHRLIYMIDENEVIIIAC
RYHYQ

Nucleotide

• Length: 258 bp

>T95056 NZ_CP026530:492466-492723 [Nautilia sp. PV-1]
ATGAAAATTGCTTTTACGCTTGAAGGCTGGGAAGATTATATATATTGGCAGAAAATTGATAAAAAAATTGTAAAAAAAAT
AAACGAATTGATTAAAGATATTAAAAGACATCCGTTTGAAGGTTTAGGCAAACCTGAAGCATTGAAATTTGATTTTGCAG
GATGTTATTCGAGAAGAATCAATCACGAACACAGACTGATATATATGATTGATGAAAATGAAGTTATAATAATCGCCTGC
AGATATCATTATCAGTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9651.15 Da
• Isoelectric Point: 9.4262

>AT95056 WP_127679630.1 NZ_CP026530:492221-492466 [Nautilia sp. PV-1]
MEVVTMSEARNNLKEIFEKVYFNHDEIIIHRKGKESVVMISLDEFNSLKETEYLMKNQANREWIKKSINNAKSGKKIYKE
I

Nucleotide

• Length: 246 bp

>AT95056 NZ_CP026530:492221-492466 [Nautilia sp. PV-1]
ATGGAAGTAGTAACGATGAGTGAAGCCAGAAATAACCTTAAAGAAATTTTTGAAAAAGTTTATTTTAATCATGATGAAAT
AATCATACACAGAAAAGGAAAAGAAAGTGTTGTGATGATTTCTCTTGATGAATTCAACTCTTTAAAAGAAACCGAATATT
TAATGAAAAACCAGGCAAACAGAGAGTGGATTAAAAAATCCATAAACAATGCGAAATCAGGTAAAAAAATCTATAAAGAA
ATATAA