Detailed information of TA system TA095039

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 53054..53694
• Replicon: plasmid unnamed1
• Accession: NZ_CP026517
• Organism: Deinococcus sp. NW-56

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: C3K08_RS14130
• Protein ID: WP_104992130.1
• Coordinates: 53054..53461 (-)
• Length: 136 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: C3K08_RS14135
• Protein ID: WP_104992131.1
• Coordinates: 53458..53694 (-)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C3K08_RS14125	51107..52576	+	1470	WP_104992129.1	glutamate synthase subunit beta	-
C3K08_RS14130	53054..53461	-	408	WP_104992130.1	type II toxin-antitoxin system VapC family toxin	Toxin
C3K08_RS14135	53458..53694	-	237	WP_104992131.1	antitoxin	Antitoxin
C3K08_RS14140	53883..54938	-	1056	WP_104992132.1	3-isopropylmalate dehydrogenase	-
C3K08_RS14145	54931..55503	-	573	WP_104992133.1	3-isopropylmalate dehydratase small subunit	-
C3K08_RS14150	55503..56792	-	1290	WP_104992134.1	3-isopropylmalate dehydratase large subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..375354	375354

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-126)

Antitoxin

• SpoVT-AbrB domain (7-45)

Sequences

Toxin

Protein

• Length: 136 a.a.
• Molecular weight: 14939.25 Da
• Isoelectric Point: 8.0818

>T95039 WP_104992130.1 NZ_CP026517:c53461-53054 [Deinococcus sp. NW-56]
MTLRYLLDTNICIFIIKNKPAAVRERFARLHSGEVGLSAVTEAELLHGVYKSMRVEHNLAAVLDFASRLVVVPFGSQVTE
TYGRIRAELERAGQPIGPLDVQIAATAVAHGLTLVTNNTREFARVPGIQLEDWTR

Nucleotide

• Length: 408 bp

>T95039 NZ_CP026517:c53461-53054 [Deinococcus sp. NW-56]
TTGACCCTCCGTTACCTCCTCGACACCAACATCTGCATCTTCATCATCAAGAACAAGCCCGCCGCCGTGCGGGAGCGGTT
TGCCAGGCTGCATTCTGGCGAGGTGGGCTTGAGCGCCGTCACCGAGGCCGAGCTGCTGCACGGGGTCTACAAAAGCATGC
GGGTGGAGCACAATCTCGCGGCCGTGCTGGACTTCGCCTCGCGACTGGTGGTGGTGCCCTTTGGTTCGCAGGTGACAGAG
ACCTATGGACGCATCCGGGCTGAGCTGGAAAGGGCCGGGCAGCCCATCGGTCCGCTGGACGTTCAGATCGCGGCCACAGC
GGTGGCCCACGGCCTGACCCTCGTGACCAACAACACCCGTGAGTTCGCACGGGTACCAGGCATTCAGCTCGAAGACTGGA
CCCGGTAG

Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 8809.00 Da
• Isoelectric Point: 5.8452

>AT95039 WP_104992131.1 NZ_CP026517:c53694-53458 [Deinococcus sp. NW-56]
MTTAKVFRSGNSQAVRLPREMRLDVREVEIIRHGDLLILRPIRREATLASAFDALAGIGDDFLPEGRQQGESQEREAF

Nucleotide

• Length: 237 bp

>AT95039 NZ_CP026517:c53694-53458 [Deinococcus sp. NW-56]
ATGACCACAGCCAAAGTCTTTCGGAGTGGCAACTCCCAGGCCGTCCGTCTGCCCCGCGAGATGCGGTTGGATGTCCGCGA
GGTCGAGATCATCCGCCACGGTGATCTGCTGATCCTCAGGCCCATTCGGAGGGAGGCGACCCTCGCCTCCGCCTTCGATG
CGTTGGCCGGGATCGGGGACGACTTCCTGCCGGAAGGCCGTCAGCAGGGCGAATCCCAGGAGCGAGAAGCCTTTTGA