Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 109195..109844 Replicon chromosome
Accession NZ_CP026516
Organism Deinococcus sp. NW-56

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C3K08_RS00610 Protein ID WP_104989577.1
Coordinates 109419..109844 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag C3K08_RS00605 Protein ID WP_104989576.1
Coordinates 109195..109422 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C3K08_RS00585 104537..105007 + 471 WP_104989572.1 peroxiredoxin -
C3K08_RS00590 105004..105423 + 420 WP_104989573.1 HIT family protein -
C3K08_RS00595 105481..107274 + 1794 WP_104989574.1 ABC transporter ATP-binding protein/permease -
C3K08_RS00600 107357..109162 + 1806 WP_104989575.1 ABC transporter ATP-binding protein/permease -
C3K08_RS00605 109195..109422 + 228 WP_104989576.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
C3K08_RS00610 109419..109844 + 426 WP_104989577.1 type II toxin-antitoxin system VapC family toxin Toxin
C3K08_RS00615 109860..110504 - 645 WP_104989578.1 phosphate signaling complex protein PhoU -
C3K08_RS00620 110555..111532 - 978 WP_104989579.1 histidine kinase -
C3K08_RS00625 111529..112218 - 690 WP_104989580.1 response regulator transcription factor -
C3K08_RS00630 112285..112680 - 396 WP_104989581.1 ribosome silencing factor -
C3K08_RS00635 112677..114026 - 1350 WP_104989582.1 LCP family protein -
C3K08_RS00640 114023..114631 - 609 WP_199776957.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15309.32 Da        Isoelectric Point: 6.8710

>T95038 WP_104989577.1 NZ_CP026516:109419-109844 [Deinococcus sp. NW-56]
MTPPPTLYLLDTNICIYTMNRRPEAVRRRLEETAAAGHALGLSSVTWHELWYGVRRSAQPEANAARLGALAGALDLYPFG
DDAAERAARIRAELSRQGRSIGPYDVLIAGHALSLGATLVTHNVGEFGRVQGLSVEDWVQG

Download         Length: 426 bp

>T95038 NZ_CP026516:109419-109844 [Deinococcus sp. NW-56]
ATGACCCCGCCGCCCACCCTCTATCTCCTCGATACCAACATCTGCATCTACACCATGAACCGCCGCCCGGAGGCGGTGCG
CCGACGGCTGGAGGAGACGGCCGCCGCCGGGCACGCGCTGGGCCTGTCCAGCGTGACCTGGCATGAACTGTGGTACGGGG
TGCGCCGCAGCGCCCAGCCGGAGGCGAACGCGGCGCGGCTCGGGGCGCTCGCCGGGGCACTCGACCTTTACCCCTTTGGC
GACGACGCGGCCGAGCGGGCCGCCCGTATCCGTGCGGAACTCTCGCGCCAGGGCCGGAGTATCGGTCCCTACGACGTGCT
GATTGCCGGGCACGCCCTGAGCCTGGGAGCCACCCTGGTCACCCACAACGTGGGCGAATTCGGCCGGGTGCAGGGGCTGA
GCGTCGAGGACTGGGTCCAGGGCTAG

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8539.73 Da        Isoelectric Point: 8.7722

>AT95038 WP_104989576.1 NZ_CP026516:109195-109422 [Deinococcus sp. NW-56]
VTRSKVFRSGNSQAVRIPRELHLPYGEVEITRRGRELVITPLPRQDGRAVFAALTAFEGMPEREQPAEQERDPLL

Download         Length: 228 bp

>AT95038 NZ_CP026516:109195-109422 [Deinococcus sp. NW-56]
GTGACCCGCAGCAAGGTCTTCCGCAGCGGCAACAGTCAGGCGGTGCGGATTCCGCGTGAGCTGCACTTGCCCTACGGCGA
GGTGGAGATCACCCGGCGTGGACGCGAACTCGTCATCACGCCGCTGCCCCGGCAGGACGGCCGCGCGGTCTTCGCGGCGC
TGACCGCCTTCGAGGGGATGCCGGAGCGCGAGCAGCCCGCCGAGCAGGAGCGCGACCCCCTGCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References