Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1924183..1924328 Replicon chromosome
Accession NZ_CP026495
Organism Klebsiella pneumoniae strain 616

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1924219..1924321 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1924183..1924328 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2861_RS09565 1919313..1921373 + 2061 WP_004148850.1 oligopeptidase B -
C2861_RS09570 1921377..1922036 - 660 WP_032435029.1 exodeoxyribonuclease X -
C2861_RS09575 1922115..1922345 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C2861_RS09580 1922458..1922832 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C2861_RS09585 1922836..1923705 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
C2861_RS09590 1923722..1924060 + 339 WP_002911404.1 YebY family protein -
- 1924183..1924328 - 146 - - Antitoxin
- 1924219..1924321 + 103 - - Toxin
C2861_RS26835 1924696..1924839 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C2861_RS09600 1924944..1925912 - 969 WP_004151446.1 VirK/YbjX family protein -
C2861_RS09605 1926069..1926722 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
C2861_RS09610 1926719..1926910 - 192 WP_002911395.1 YebW family protein -
C2861_RS09615 1927008..1927247 - 240 WP_002911393.1 YebV family protein -
C2861_RS09620 1927363..1928796 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T95017 NZ_CP026495:1924219-1924321 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT95017 NZ_CP026495:c1924328-1924183 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References