Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 16894..17462 Replicon plasmid pAER-f133
Accession NZ_CP026408
Organism Aeromonas sp. ASNIH2

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag C3F36_RS23010 Protein ID WP_059167471.1
Coordinates 17169..17462 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C3F36_RS23005 Protein ID WP_104456134.1
Coordinates 16894..17181 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C3F36_RS22975 12384..12596 - 213 WP_104456128.1 Rop family plasmid primer RNA-binding protein -
C3F36_RS22980 12908..14137 - 1230 WP_104456129.1 plasmid recombination protein -
C3F36_RS22985 14346..14588 + 243 WP_104456130.1 plasmid replication protein RepB -
C3F36_RS22990 14603..14812 + 210 WP_104456131.1 hypothetical protein -
C3F36_RS23505 14809..14958 + 150 WP_158003968.1 hypothetical protein -
C3F36_RS22995 15842..16039 - 198 WP_104456132.1 chromosome partitioning protein ParB -
C3F36_RS23000 16060..16689 - 630 WP_104456133.1 AAA family ATPase -
C3F36_RS23005 16894..17181 + 288 WP_104456134.1 CopG family ribbon-helix-helix protein Antitoxin
C3F36_RS23010 17169..17462 + 294 WP_059167471.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C3F36_RS23510 17675..18016 + 342 WP_158656191.1 hypothetical protein -
C3F36_RS23015 18097..18486 - 390 WP_104456135.1 hypothetical protein -
C3F36_RS23020 18674..18943 - 270 WP_059167473.1 hypothetical protein -
C3F36_RS23025 19133..20212 + 1080 WP_059167481.1 CZB domain-containing protein -
C3F36_RS23520 20379..20555 - 177 WP_158003970.1 hypothetical protein -
C3F36_RS23030 20859..22229 + 1371 WP_104456136.1 mobilization protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katB 1..29979 29979


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11010.87 Da        Isoelectric Point: 11.2805

>T94839 WP_059167471.1 NZ_CP026408:17169-17462 [Aeromonas sp. ASNIH2]
MPPVIFAPAALRDLQRLREFLRPKSQQVAQRAATTIQLSLRQLAAQPSMGRPIKGLPEAFREWVIPFGDSGYLARYRIEP
DVIVVLAVRHQREVGYS

Download         Length: 294 bp

>T94839 NZ_CP026408:17169-17462 [Aeromonas sp. ASNIH2]
ATGCCACCAGTGATCTTTGCCCCTGCAGCCTTGCGAGACTTGCAACGCCTACGTGAATTCCTGCGCCCTAAAAGCCAGCA
GGTCGCACAGCGGGCAGCAACAACAATCCAGCTGTCCCTACGCCAGCTCGCAGCCCAACCCTCAATGGGCCGCCCCATTA
AAGGACTACCAGAGGCGTTTCGTGAGTGGGTGATCCCCTTTGGAGACAGCGGCTATTTAGCCCGCTATCGCATTGAACCG
GACGTTATCGTGGTGCTCGCTGTCCGCCATCAGCGCGAAGTGGGCTACTCATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 11066.20 Da        Isoelectric Point: 4.7118

>AT94839 WP_104456134.1 NZ_CP026408:16894-17181 [Aeromonas sp. ASNIH2]
MPTQSKPVSIKLDADTQERIKRLATSRERSAHWLMREAISQYVEREELRETFQRDTLEAWQEFQETGRYATAQDVDQWLA
SWGTDAEGAPPACHQ

Download         Length: 288 bp

>AT94839 NZ_CP026408:16894-17181 [Aeromonas sp. ASNIH2]
ATGCCCACACAATCCAAACCGGTCTCAATAAAACTCGACGCCGACACCCAGGAACGCATCAAACGCTTGGCAACCTCCCG
CGAACGCTCTGCCCATTGGCTCATGCGCGAAGCAATCAGCCAGTACGTCGAACGCGAAGAACTGCGCGAGACCTTCCAGC
GTGACACTCTGGAGGCCTGGCAGGAGTTCCAGGAGACTGGCCGTTATGCCACCGCTCAAGATGTGGATCAGTGGCTAGCC
TCTTGGGGCACTGATGCCGAAGGAGCGCCTCCGGCATGCCACCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References