Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4952773..4952918 Replicon chromosome
Accession NZ_CP026392
Organism Klebsiella pneumoniae strain KPNIH48

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4952809..4952911 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4952773..4952918 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C3F39_RS25455 4947903..4949963 + 2061 WP_004151449.1 oligopeptidase B -
C3F39_RS25460 4949967..4950626 - 660 WP_021440386.1 exodeoxyribonuclease X -
C3F39_RS25465 4950705..4950935 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C3F39_RS25470 4951048..4951422 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C3F39_RS25475 4951426..4952295 + 870 WP_064172307.1 copper homeostasis membrane protein CopD -
C3F39_RS25480 4952312..4952650 + 339 WP_002911404.1 YebY family protein -
- 4952773..4952918 - 146 - - Antitoxin
- 4952809..4952911 + 103 - - Toxin
C3F39_RS33775 4953285..4953428 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C3F39_RS25490 4953533..4954501 - 969 WP_004151446.1 VirK/YbjX family protein -
C3F39_RS25495 4954658..4955311 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
C3F39_RS25500 4955308..4955499 - 192 WP_002911395.1 YebW family protein -
C3F39_RS25505 4955597..4955836 - 240 WP_002911393.1 YebV family protein -
C3F39_RS25510 4955952..4957385 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4881027..4970314 89287


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T94779 NZ_CP026392:4952809-4952911 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT94779 NZ_CP026392:c4952918-4952773 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References