Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 954720..955291 Replicon chromosome
Accession NZ_CP026383
Organism Serratia sp. SSNIH1

Toxin (Protein)


Gene name relE Uniprot ID A0A0G3SNA4
Locus tag C3F38_RS04565 Protein ID WP_038879053.1
Coordinates 955016..955291 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A086G7I5
Locus tag C3F38_RS04560 Protein ID WP_013811307.1
Coordinates 954720..955007 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C3F38_RS04535 950489..951574 - 1086 WP_033636846.1 carbon-phosphorus lyase complex subunit PhnI -
C3F38_RS04540 951574..952155 - 582 WP_055317326.1 phosphonate C-P lyase system protein PhnH -
C3F38_RS04545 952159..952602 - 444 WP_055317625.1 phosphonate C-P lyase system protein PhnG -
C3F38_RS04550 952603..953331 - 729 WP_015376439.1 phosphonate metabolism transcriptional regulator PhnF -
C3F38_RS04555 953559..954614 + 1056 WP_055312195.1 permease -
C3F38_RS04560 954720..955007 + 288 WP_013811307.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
C3F38_RS04565 955016..955291 + 276 WP_038879053.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
C3F38_RS04570 955297..955761 - 465 WP_038879049.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
C3F38_RS04580 955929..958067 - 2139 WP_055312197.1 anaerobic ribonucleoside-triphosphate reductase -
C3F38_RS04585 958312..959226 - 915 WP_047729215.1 LysR family transcriptional regulator -
C3F38_RS04590 959333..959857 + 525 WP_055317379.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-70)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10736.52 Da        Isoelectric Point: 9.5103

>T94747 WP_038879053.1 NZ_CP026383:955016-955291 [Serratia sp. SSNIH1]
MRIEWDNAALRDRERIFEFLYIFNPQAAVQADNEIDKAVKRLLDHPELGKPWYGKARKLLINKASLLLVYIIVDDVIKVF
SIAHQREKFPN

Download         Length: 276 bp

>T94747 NZ_CP026383:955016-955291 [Serratia sp. SSNIH1]
ATGCGTATCGAATGGGATAATGCAGCGCTACGGGACAGGGAACGTATTTTTGAGTTTCTTTATATTTTCAATCCACAGGC
GGCAGTGCAGGCTGATAACGAGATAGATAAAGCGGTAAAGCGTTTGCTGGATCATCCTGAGTTAGGTAAGCCTTGGTATG
GGAAGGCACGTAAGTTGCTAATTAACAAGGCCTCCCTGTTGCTGGTGTATATCATCGTCGATGATGTTATTAAGGTTTTC
TCGATTGCCCACCAGCGTGAGAAATTTCCAAACTAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 11032.33 Da        Isoelectric Point: 5.8001

>AT94747 WP_013811307.1 NZ_CP026383:954720-955007 [Serratia sp. SSNIH1]
MESRIQFRIEDETKRLAQKAAEAKGTTLSEACRRLAEQMADEQRAAEEHENWLKDKVDAAFSRLHEGNAVYLSQQEVEES
MDAFKAKIRAKYDRK

Download         Length: 288 bp

>AT94747 NZ_CP026383:954720-955007 [Serratia sp. SSNIH1]
ATGGAAAGTCGCATCCAGTTTCGCATCGAAGATGAAACCAAGCGTTTGGCGCAAAAGGCCGCGGAAGCTAAAGGAACGAC
ATTGAGTGAAGCCTGCCGCCGTTTGGCGGAGCAAATGGCTGATGAGCAACGGGCCGCGGAGGAGCACGAAAATTGGTTGA
AAGATAAGGTGGATGCAGCTTTTTCCCGTCTGCATGAGGGTAATGCTGTCTACCTTAGCCAACAAGAAGTTGAAGAAAGC
ATGGATGCCTTTAAGGCAAAAATTAGAGCGAAATACGACCGAAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0G3SNA4

Antitoxin

Source ID Structure
AlphaFold DB A0A086G7I5

References