Detailed information of TA system TA094744

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 537539..538074
• Replicon: chromosome
• Accession: NZ_CP026383
• Organism: Serratia sp. SSNIH1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C3F38_RS02555
• Protein ID: WP_055317499.1
• Coordinates: 537799..538074 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A5P6GNG1
• Locus tag: C3F38_RS02550
• Protein ID: WP_038875948.1
• Coordinates: 537539..537799 (+)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C3F38_RS02530	532859..533509	+	651	WP_047729554.1	DcrB-related protein	-
C3F38_RS02535	533550..534155	+	606	WP_038875954.1	glutathione S-transferase	-
C3F38_RS02540	534224..535618	+	1395	WP_047729550.1	L-seryl-tRNA(Sec) selenium transferase	-
C3F38_RS02545	535615..537456	+	1842	WP_055317498.1	selenocysteine-specific translation elongation factor	-
C3F38_RS02550	537539..537799	+	261	WP_038875948.1	ribbon-helix-helix domain-containing protein	Antitoxin
C3F38_RS02555	537799..538074	+	276	WP_055317499.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C3F38_RS02560	538086..538997	-	912	WP_038875943.1	LysR family transcriptional regulator	-
C3F38_RS02565	539119..539745	+	627	WP_055317500.1	LysE family translocator	-
C3F38_RS02570	539798..541045	-	1248	WP_038875940.1	MFS transporter	-
C3F38_RS02575	541263..542255	+	993	WP_038875938.1	acyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (6-43)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10534.31 Da
• Isoelectric Point: 10.6099

>T94744 WP_055317499.1 NZ_CP026383:537799-538074 [Serratia sp. SSNIH1]
MALKWTSKALSDLARLFEFLALANRTVAANSVKGLVAAPKALLDNPRLGERLDEFLPQEVRRILVGRYEIRYQVQPATIY
VLRIWHTREER

Nucleotide

• Length: 276 bp

>T94744 NZ_CP026383:537799-538074 [Serratia sp. SSNIH1]
ATGGCGTTAAAATGGACGAGTAAGGCGCTATCGGATTTGGCGCGTTTGTTTGAGTTTCTTGCCTTGGCTAACCGCACTGT
GGCAGCGAATTCGGTGAAGGGCTTGGTCGCCGCGCCTAAAGCGTTGCTTGATAATCCTCGCCTGGGTGAAAGACTGGATG
AGTTTTTACCGCAGGAAGTGAGACGTATTCTGGTCGGCCGTTATGAGATACGTTACCAGGTGCAGCCGGCAACGATTTAT
GTTCTGCGTATTTGGCATACCCGCGAAGAGCGATAG

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9667.98 Da
• Isoelectric Point: 4.5201

>AT94744 WP_038875948.1 NZ_CP026383:537539-537799 [Serratia sp. SSNIH1]
MNTKVITAHVPLPLAEKVDEMAAKLERSRGWIVKQALAAWLEQEEERRRLTLAALADVEQQNVIDHESVEAWAASLDSDD
PLPVPR

Nucleotide

• Length: 261 bp

>AT94744 NZ_CP026383:537539-537799 [Serratia sp. SSNIH1]
ATGAATACGAAAGTCATCACCGCTCATGTGCCGCTGCCTTTGGCTGAAAAGGTGGATGAAATGGCCGCCAAACTTGAACG
TTCACGGGGATGGATAGTGAAACAAGCCCTCGCCGCCTGGCTCGAGCAAGAGGAAGAGCGCCGTCGGTTAACGCTGGCGG
CGTTGGCCGATGTCGAACAGCAAAACGTTATCGATCATGAGTCGGTAGAAGCCTGGGCTGCCAGCCTGGACAGTGACGAT
CCGCTGCCGGTACCGCGCTGA

Structures

Antitoxin

• AlphaFold DB: A0A5P6GNG1