Detailed information of TA system TA094741

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-pasA/RelE-HTH
• Location: 3473694..3474156
• Replicon: chromosome
• Accession: NZ_CP026381
• Organism: Sphingopyxis sp. MG

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C3E99_RS16005
• Protein ID: WP_076077237.1
• Coordinates: 3473887..3474156 (+)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: C3E99_RS16000
• Protein ID: WP_199775123.1
• Coordinates: 3473694..3473903 (+)
• Length: 70 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C3E99_RS15980	3469142..3469432	+	291	WP_104960115.1	GIY-YIG nuclease family protein	-
C3E99_RS15985	3469667..3472636	+	2970	WP_104960116.1	isoleucine--tRNA ligase	-
C3E99_RS15990	3472633..3473166	+	534	WP_067111424.1	signal peptidase II	-
C3E99_RS15995	3473194..3473613	+	420	WP_067111427.1	DUF3035 domain-containing protein	-
C3E99_RS16000	3473694..3473903	+	210	WP_199775123.1	TraY domain-containing protein	Antitoxin
C3E99_RS16005	3473887..3474156	+	270	WP_076077237.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C3E99_RS16010	3474175..3476103	-	1929	WP_076077239.1	1-deoxy-D-xylulose-5-phosphate synthase	-
C3E99_RS19890	3476165..3476413	-	249	WP_076077242.1	hypothetical protein	-
C3E99_RS16020	3476705..3477712	+	1008	WP_158682340.1	MipA/OmpV family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-86)

Antitoxin

• Protein of unknown function DUF6290 (1-65)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10306.01 Da
• Isoelectric Point: 11.5446

>T94741 WP_076077237.1 NZ_CP026381:3473887-3474156 [Sphingopyxis sp. MG]
MAWTLEFDAAARRQLRKLPRSAGERILAGLEQVAALENPRQRGKALVGERTGYWRYRIGDYRVIAKIEDGRMVILVVAIG
HRREIYRRA

Nucleotide

• Length: 270 bp

>T94741 NZ_CP026381:3473887-3474156 [Sphingopyxis sp. MG]
TTGGCCTGGACGCTTGAGTTCGACGCGGCGGCCCGGCGGCAACTCCGCAAGCTGCCGCGCAGCGCCGGCGAGCGCATCCT
TGCCGGGCTGGAGCAGGTCGCCGCACTCGAAAACCCGCGCCAGCGCGGCAAGGCGCTAGTCGGCGAACGCACCGGCTATT
GGCGCTATCGCATCGGCGATTATCGCGTGATCGCAAAGATAGAGGACGGCCGAATGGTGATCCTCGTCGTCGCGATCGGC
CACCGGCGCGAGATTTATCGACGCGCTTGA

Antitoxin

Protein

• Length: 70 a.a.
• Molecular weight: 7764.79 Da
• Isoelectric Point: 4.5348

>AT94741 WP_199775123.1 NZ_CP026381:3473694-3473903 [Sphingopyxis sp. MG]
IRLDKELEERLAAAARRSGRTKTALARKAIEEYIEDLEDIALLEEALNQPDAGKTVSIEQMRRELGLDA

Nucleotide

• Length: 210 bp

>AT94741 NZ_CP026381:3473694-3473903 [Sphingopyxis sp. MG]
ATCCGCCTCGACAAGGAATTGGAAGAACGGCTCGCCGCCGCCGCCAGGCGGTCGGGCCGGACCAAGACCGCCCTCGCGCG
CAAGGCGATCGAGGAATATATCGAGGACCTCGAAGATATCGCGCTTCTCGAAGAAGCGTTGAATCAGCCCGACGCAGGCA
AGACCGTTTCGATCGAACAGATGCGACGCGAGCTTGGCCTGGACGCTTGA