Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 3465737..3466380 Replicon chromosome
Accession NZ_CP026378
Organism Mixta calida strain DSM 22759

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag C2E16_RS16565 Protein ID WP_038624510.1
Coordinates 3465964..3466380 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag C2E16_RS16560 Protein ID WP_084970331.1
Coordinates 3465737..3465967 (+) Length 77 a.a.

Genomic Context

C2E16_RS16545C2E16_RS16555C2E16_RS16560C2E16_RS16565C2E16_RS16575C2E16_RS20625C2E16_RS16550C2E16_RS16570C2E16_RS20900C2E16_RS16590
Location: 3461038..3461925 (888 bp)
Type: Others
Protein ID: WP_084970329.1
Location: 3462626..3465193 (2568 bp)
Type: Others
Protein ID: WP_174705333.1
Location: 3465737..3465967 (231 bp)
Type: Antitoxin
Protein ID: WP_084970331.1
Location: 3465964..3466380 (417 bp)
Type: Toxin
Protein ID: WP_038624510.1
Location: 3467595..3468986 (1392 bp)
Type: Others
Protein ID: WP_038624508.1
Location: 3469386..3469826 (441 bp)
Type: Others
Protein ID: WP_133052060.1
Location: 3461996..3462337 (342 bp)
Type: Others
Protein ID: WP_038624517.1
Location: 3466569..3467471 (903 bp)
Type: Others
Protein ID: WP_038629895.1
Location: 3470048..3470203 (156 bp)
Type: Others
Protein ID: WP_156462399.1
Location: 3470265..3470681 (417 bp)
Type: Others
Protein ID: WP_084970333.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
C2E16_RS165453461038..3461925+888WP_084970329.1dihydrodipicolinate synthase family protein-
C2E16_RS165503461996..3462337-342WP_038624517.1alkylphosphonate utilization protein-
C2E16_RS165553462626..3465193+2568WP_174705333.1DNA mismatch repair protein MutS-
C2E16_RS165603465737..3465967+231WP_084970331.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
C2E16_RS165653465964..3466380+417WP_038624510.1type II toxin-antitoxin system VapC family toxinToxin
C2E16_RS165703466569..3467471-903WP_038629895.1LysR family transcriptional regulator-
C2E16_RS165753467595..3468986+1392WP_038624508.1MFS transporter-
C2E16_RS206253469386..3469826+441WP_133052060.1hypothetical protein-
C2E16_RS209003470048..3470203-156WP_156462399.1hypothetical protein-
C2E16_RS165903470265..3470681-417WP_084970333.1GNAT family N-acetyltransferase-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-128)

Antitoxin

SpoVT-AbrB domain

(7-52)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14921.26 Da        Isoelectric Point: 6.8621

>T94737 WP_038624510.1 NZ_CP026378:3465964-3466380 [Mixta calida]
VIKTYMLDTNICSFIMREQPEAVIKRLEQAVLRNHRIVVSAITYAEMRFGAIGKKASPRHGLLVEAFCARLDAILSWDRA
AVDATTEIKAALTAAGTPIGPNDTAIAGHAIAAGAVLVTNNVREFEHVPGLVLEDWAN

Download         Length: 417 bp

>T94737 NZ_CP026378:3465964-3466380 [Mixta calida]
GTGATCAAGACCTATATGCTGGACACCAACATTTGCTCCTTCATCATGCGTGAGCAGCCGGAAGCTGTCATTAAACGGCT
GGAACAGGCAGTACTGCGCAATCATCGTATCGTGGTTTCGGCCATCACCTATGCCGAGATGCGTTTCGGTGCGATCGGAA
AGAAGGCATCTCCCCGCCATGGCTTGCTCGTCGAAGCTTTCTGCGCCCGTCTCGATGCAATCCTCTCCTGGGATCGCGCC
GCGGTGGACGCAACCACAGAGATTAAGGCCGCGCTGACTGCGGCCGGGACGCCAATCGGTCCGAACGACACGGCGATTGC
CGGGCATGCCATCGCCGCCGGCGCCGTACTGGTGACGAACAACGTGCGAGAGTTTGAGCATGTGCCTGGGCTGGTTCTGG
AAGACTGGGCTAACTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8685.75 Da        Isoelectric Point: 4.4563

>AT94737 WP_084970331.1 NZ_CP026378:3465737-3465967 [Mixta calida]
MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIIREGDSIILRPVRPTWGSFTQLEKADSDFMAERGDVVSDEGRFDL

Download         Length: 231 bp

>AT94737 NZ_CP026378:3465737-3465967 [Mixta calida]
ATGAGAACCGTATCAATATTCAAAAACGGCAATAATCGCGCTATCCGTCTGCCCCGAGACCTGGATTTTGAGGGAGTGAG
CGAACTGGAGATCATCCGGGAAGGTGACAGCATTATCCTTCGTCCCGTTCGCCCAACATGGGGTTCGTTTACTCAGCTCG
AAAAAGCCGATTCAGACTTTATGGCCGAGCGTGGGGACGTCGTCAGCGATGAAGGACGGTTTGACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References