Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3267010..3267644 Replicon chromosome
Accession NZ_CP026378
Organism Mixta calida strain DSM 22759

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C2E16_RS15540 Protein ID WP_084971120.1
Coordinates 3267010..3267414 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C2E16_RS15545 Protein ID WP_038624739.1
Coordinates 3267414..3267644 (-) Length 77 a.a.

Genomic Context

C2E16_RS15520C2E16_RS15530C2E16_RS15535C2E16_RS15560C2E16_RS15525C2E16_RS15540C2E16_RS15545C2E16_RS15550C2E16_RS15555
Location: 3262091..3262696 (606 bp)
Type: Others
Protein ID: WP_084971118.1
Location: 3265174..3265359 (186 bp)
Type: Others
Protein ID: WP_038624745.1
Location: 3265472..3266899 (1428 bp)
Type: Others
Protein ID: WP_038624743.1
Location: 3271220..3272590 (1371 bp)
Type: Others
Protein ID: WP_038624733.1
Location: 3262697..3264850 (2154 bp)
Type: Others
Protein ID: WP_052134006.1
Location: 3267010..3267414 (405 bp)
Type: Toxin
Protein ID: WP_084971120.1
Location: 3267414..3267644 (231 bp)
Type: Antitoxin
Protein ID: WP_038624739.1
Location: 3267932..3269512 (1581 bp)
Type: Others
Protein ID: WP_038624737.1
Location: 3269584..3271050 (1467 bp)
Type: Others
Protein ID: WP_038624735.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
C2E16_RS155203262091..3262696+606WP_084971118.1tellurite resistance methyltransferase TehB-
C2E16_RS155253262697..3264850-2154WP_052134006.1sensor domain-containing phosphodiesterase-
C2E16_RS155303265174..3265359+186WP_038624745.1DUF2633 family protein-
C2E16_RS155353265472..3266899+1428WP_038624743.1magnesium transporter-
C2E16_RS155403267010..3267414-405WP_084971120.1tRNA(fMet)-specific endonuclease VapCToxin
C2E16_RS155453267414..3267644-231WP_038624739.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
C2E16_RS155503267932..3269512-1581WP_038624737.1glutamine-hydrolyzing GMP synthase-
C2E16_RS155553269584..3271050-1467WP_038624735.1IMP dehydrogenase-
C2E16_RS155603271220..3272590+1371WP_038624733.1exodeoxyribonuclease VII large subunit-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14972.27 Da        Isoelectric Point: 7.8710

>T94736 WP_084971120.1 NZ_CP026378:c3267414-3267010 [Mixta calida]
MLKYMLDTNICIYTIKNKPPTVRTAFNQRYGQLCVSSVTLMELIYEAEKSASPEKNLRVVEGFIARLEVLNYSNEAAIHT
GQIRAELAKAGTPVGPYDSMIAAHARSLGLILVTNNTHEFVRISGLRLEDWSVN

Download         Length: 405 bp

>T94736 NZ_CP026378:c3267414-3267010 [Mixta calida]
ATGCTCAAATATATGTTGGATACCAACATCTGTATTTATACCATTAAAAACAAGCCTCCGACTGTGCGCACCGCTTTTAA
TCAACGTTATGGACAGCTGTGCGTCAGTTCCGTAACGCTAATGGAACTGATCTACGAAGCGGAGAAATCTGCCAGCCCGG
AAAAAAATCTGCGGGTAGTAGAAGGCTTTATCGCCAGGCTGGAAGTATTAAATTATAGTAACGAGGCTGCAATCCATACG
GGGCAAATTCGTGCGGAGCTGGCGAAAGCGGGGACGCCGGTCGGTCCGTATGACAGTATGATCGCGGCGCATGCCCGATC
GCTGGGGCTGATTCTGGTCACCAATAATACACACGAATTTGTCAGAATCTCCGGGCTGCGCCTGGAGGACTGGAGCGTTA
ATTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8585.50 Da        Isoelectric Point: 4.2821

>AT94736 WP_038624739.1 NZ_CP026378:c3267644-3267414 [Mixta calida]
MEKTTVFKNNRSQAVRLPKAVALPDNVSQVEIIAVGRTRIITPAGEGWDSWFDGEDVTSDFMTARDQPDEQERESF

Download         Length: 231 bp

>AT94736 NZ_CP026378:c3267644-3267414 [Mixta calida]
ATGGAAAAGACGACCGTGTTTAAAAACAATCGCAGCCAGGCGGTGCGTTTGCCTAAAGCCGTCGCGCTGCCGGACAATGT
CAGCCAGGTTGAAATTATTGCCGTGGGCCGGACGCGGATAATTACGCCCGCAGGCGAGGGTTGGGATAGCTGGTTTGATG
GAGAGGACGTAACATCAGATTTTATGACGGCACGGGATCAGCCTGATGAACAAGAAAGGGAAAGCTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References