Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3677193..3677856 Replicon chromosome
Accession NZ_CP026377
Organism Mixta gaviniae strain DSM 22758

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag C2E15_RS17200 Protein ID WP_167391893.1
Coordinates 3677193..3677573 (-) Length 127 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag C2E15_RS17205 Protein ID WP_085070265.1
Coordinates 3677578..3677856 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2E15_RS17180 3673190..3674920 - 1731 WP_104958444.1 single-stranded-DNA-specific exonuclease RecJ -
C2E15_RS17185 3674927..3675631 - 705 WP_104958445.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
C2E15_RS17190 3675657..3676550 - 894 WP_104958446.1 site-specific tyrosine recombinase XerD -
C2E15_RS17195 3676658..3677176 + 519 WP_104959226.1 flavodoxin FldB -
C2E15_RS17200 3677193..3677573 - 381 WP_167391893.1 hypothetical protein Toxin
C2E15_RS17205 3677578..3677856 - 279 WP_085070265.1 FAD assembly factor SdhE Antitoxin
C2E15_RS17210 3678083..3679066 + 984 WP_104958448.1 tRNA-modifying protein YgfZ -
C2E15_RS17215 3679109..3679768 - 660 WP_104958449.1 hemolysin III family protein -
C2E15_RS17220 3679987..3680718 + 732 WP_104958450.1 MurR/RpiR family transcriptional regulator -
C2E15_RS17225 3680933..3682372 + 1440 WP_104958451.1 6-phospho-beta-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-123)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 14778.64 Da        Isoelectric Point: 12.2461

>T94734 WP_167391893.1 NZ_CP026377:c3677573-3677193 [Mixta gaviniae]
MPSARAQQITCLLYTPLVVGLLLVPWRAMQAPLMGALLLLIFGELWHRLRLQRRFSGRLTAEESRLWRWRQQDYQVARPP
FILPFGILFALRTPQGKRLSLWLMRDSMPEANWRALRRLLKGQEAG

Download         Length: 381 bp

>T94734 NZ_CP026377:c3677573-3677193 [Mixta gaviniae]
TTGCCATCGGCGCGGGCGCAGCAGATAACCTGCCTGCTCTACACTCCGCTGGTCGTTGGGCTGCTGCTGGTGCCCTGGCG
GGCAATGCAGGCGCCGTTGATGGGGGCGCTGCTGTTGCTGATCTTCGGCGAGCTGTGGCACCGTCTGCGGCTGCAGCGCC
GCTTCAGCGGCCGCCTGACGGCGGAAGAGAGCCGCCTCTGGCGCTGGCGGCAGCAGGATTATCAGGTGGCGCGCCCGCCG
TTTATTCTGCCGTTCGGCATCCTCTTTGCGCTGCGCACGCCGCAGGGCAAACGGCTTTCTCTGTGGTTGATGCGCGACAG
CATGCCGGAAGCGAACTGGCGCGCGCTGCGTCGCCTGTTAAAAGGGCAGGAGGCAGGCTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10795.36 Da        Isoelectric Point: 5.1222

>AT94734 WP_085070265.1 NZ_CP026377:c3677856-3677578 [Mixta gaviniae]
MDINDKSRIHWACRRGMLELDIAIMPFFKYEYDSLSDDDKALFIRLLKSDDPDLFNWLMNHGEPADAELKRMVQLIQTRN
QQRGPERGAVAI

Download         Length: 279 bp

>AT94734 NZ_CP026377:c3677856-3677578 [Mixta gaviniae]
ATGGATATCAACGATAAATCCCGTATTCACTGGGCCTGCCGCCGCGGCATGCTGGAGCTGGATATCGCCATTATGCCCTT
CTTTAAATATGAATATGATTCGCTGAGCGACGACGACAAGGCGCTGTTTATTCGCCTGTTGAAAAGTGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCGAGCCGGCTGACGCCGAACTGAAACGCATGGTGCAGCTGATCCAGACGCGCAAC
CAGCAGCGTGGCCCGGAACGTGGCGCGGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References