Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1301816..1302444 Replicon chromosome
Accession NZ_CP026377
Organism Mixta gaviniae strain DSM 22758

Toxin (Protein)


Gene name Hha Uniprot ID A0A2K1QC31
Locus tag C2E15_RS05975 Protein ID WP_071883698.1
Coordinates 1301816..1302034 (-) Length 73 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag C2E15_RS05980 Protein ID WP_104956558.1
Coordinates 1302064..1302444 (-) Length 127 a.a.

Genomic Context

C2E15_RS05945C2E15_RS05950C2E15_RS05960C2E15_RS05955C2E15_RS05965C2E15_RS05975C2E15_RS05980C2E15_RS05985C2E15_RS05990C2E15_RS05995C2E15_RS06000
Location: 1297783..1298121 (339 bp)
Type: Others
Protein ID: WP_104956553.1
Location: 1298158..1299441 (1284 bp)
Type: Others
Protein ID: WP_104956554.1
Location: 1300570..1301130 (561 bp)
Type: Others
Protein ID: WP_104956556.1
Location: 1299496..1300356 (861 bp)
Type: Others
Protein ID: WP_104956555.1
Location: 1301163..1301471 (309 bp)
Type: Others
Protein ID: WP_104956557.1
Location: 1301816..1302034 (219 bp)
Type: Toxin
Protein ID: WP_071883698.1
Location: 1302064..1302444 (381 bp)
Type: Antitoxin
Protein ID: WP_104956558.1
Location: 1302592..1302945 (354 bp)
Type: Others
Protein ID: WP_104956559.1
Location: 1303293..1303433 (141 bp)
Type: Others
Protein ID: WP_104956560.1
Location: 1303443..1303700 (258 bp)
Type: Others
Protein ID: WP_104956561.1
Location: 1304184..1307333 (3150 bp)
Type: Others
Protein ID: WP_104956562.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
C2E15_RS059451297783..1298121+339WP_104956553.1P-II family nitrogen regulator-
C2E15_RS059501298158..1299441+1284WP_104956554.1ammonium transporter AmtB-
C2E15_RS059551299496..1300356-861WP_104956555.1acyl-CoA thioesterase II-
C2E15_RS059601300570..1301130+561WP_104956556.1YbaY family lipoprotein-
C2E15_RS059651301163..1301471-309WP_104956557.1MGMT family protein-
C2E15_RS059751301816..1302034-219WP_071883698.1hemolysin expression modulator HhaToxin
C2E15_RS059801302064..1302444-381WP_104956558.1Hha toxicity modulator TomBAntitoxin
C2E15_RS059851302592..1302945-354WP_104956559.1hypothetical protein-
C2E15_RS059901303293..1303433-141WP_104956560.1type B 50S ribosomal protein L36-
C2E15_RS059951303443..1303700-258WP_104956561.1type B 50S ribosomal protein L31-
C2E15_RS060001304184..1307333-3150WP_104956562.1multidrug efflux RND transporter permease subunit AcrB-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(13-69)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8701.16 Da        Isoelectric Point: 8.8578

>T94733 WP_071883698.1 NZ_CP026377:c1302034-1301816 [Mixta gaviniae]
MTEKIMTKTDYLMRLRRCRSIDTLERVIEKNKYELPDDELAVFYSAADHRLAELTMNKLYDKVPVSVWKYVR

Download         Length: 219 bp

>T94733 NZ_CP026377:c1302034-1301816 [Mixta gaviniae]
ATGACAGAAAAAATTATGACCAAAACTGACTATCTGATGCGCTTAAGACGTTGCAGATCAATCGATACGCTTGAGCGGGT
GATCGAAAAGAATAAATATGAATTGCCTGATGATGAACTGGCTGTTTTTTATTCTGCGGCCGATCATCGGCTGGCGGAAT
TAACCATGAATAAGCTGTACGATAAAGTACCGGTTTCGGTGTGGAAATACGTTCGTTGA

Antitoxin


Download         Length: 127 a.a.        Molecular weight: 14755.38 Da        Isoelectric Point: 4.3024

>AT94733 WP_104956558.1 NZ_CP026377:c1302444-1302064 [Mixta gaviniae]
MDEYSPKRHDIAQLNFLCENLYDESMATLGDSHHGWVNDPTSATNLQLNELIEHIASFTMNYKIKHAEDEDLIVQIDDYL
DDTFMLFSNYGINVQDLQRWQRSARRLFNLFAEECAQLPLQPSHSF

Download         Length: 381 bp

>AT94733 NZ_CP026377:c1302444-1302064 [Mixta gaviniae]
ATGGACGAATATTCACCGAAACGGCATGATATTGCCCAGCTCAATTTCTTGTGTGAAAATCTGTACGACGAAAGTATGGC
CACGCTGGGTGACAGCCACCATGGCTGGGTCAACGATCCTACATCTGCGACCAACTTACAGCTGAATGAGCTGATTGAAC
ATATTGCTTCATTCACTATGAATTACAAAATAAAACATGCTGAAGATGAGGATCTCATCGTCCAGATCGATGACTACCTC
GACGATACCTTTATGTTATTCAGTAATTACGGCATTAATGTTCAGGATCTGCAACGTTGGCAACGTTCCGCCCGACGTTT
GTTTAATCTTTTCGCGGAAGAGTGCGCTCAGCTTCCTTTACAGCCAAGCCATTCATTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A2K1QC31

Antitoxin

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Source
ID
Structure
No matching records found

References