93839

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4855137..4855498 Replicon chromosome
Accession NZ_CP026334
Organism Xanthomonas citri pv. glycines strain EB08

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag C2859_RS22205 Protein ID WP_005914328.1
Coordinates 4855137..4855271 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag C2859_RS22210 Protein ID WP_003486606.1
Coordinates 4855346..4855498 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2859_RS22185 4850288..4851979 - 1692 WP_029829576.1 M20/M25/M40 family metallo-hydrolase -
C2859_RS22190 4852171..4853205 - 1035 WP_016850772.1 MBL fold metallo-hydrolase -
C2859_RS22195 4853244..4854533 - 1290 WP_016850773.1 tryptophan--tRNA ligase -
C2859_RS22200 4854701..4854910 - 210 WP_003486601.1 CsbD family protein -
C2859_RS22205 4855137..4855271 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
C2859_RS22210 4855346..4855498 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
C2859_RS22215 4855605..4856528 - 924 WP_003486608.1 arginase -
C2859_RS22220 4856849..4857301 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
C2859_RS22225 4857365..4857724 + 360 WP_003486613.1 hypothetical protein -
C2859_RS22230 4857821..4858738 + 918 WP_016850774.1 hypothetical protein -
C2859_RS22235 4858735..4859277 + 543 WP_003486615.1 GTPase -
C2859_RS22245 4859715..4860398 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T93839 WP_005914328.1 NZ_CP026334:c4855271-4855137 [Xanthomonas citri pv. glycines]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T93839 NZ_CP026334:c4855271-4855137 [Xanthomonas citri pv. glycines]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGTTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT93839 WP_003486606.1 NZ_CP026334:c4855498-4855346 [Xanthomonas citri pv. glycines]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT93839 NZ_CP026334:c4855498-4855346 [Xanthomonas citri pv. glycines]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References