Detailed information of TA system TA093838

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 99347..99891
• Replicon: chromosome
• Accession: NZ_CP026334
• Organism: Xanthomonas citri pv. glycines strain EB08

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C2859_RS00445
• Protein ID: WP_005928957.1
• Coordinates: 99592..99891 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A1D9ED60
• Locus tag: C2859_RS00440
• Protein ID: WP_016849693.1
• Coordinates: 99347..99604 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C2859_RS00425	94436..95947	-	1512	WP_149990058.1	ribonuclease H-like domain-containing protein	-
C2859_RS00430	95944..98439	-	2496	WP_016849694.1	DEAD/DEAH box helicase	-
C2859_RS00435	98617..99279	+	663	WP_005912558.1	hemolysin III family protein	-
C2859_RS00440	99347..99604	+	258	WP_016849693.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
C2859_RS00445	99592..99891	+	300	WP_005928957.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C2859_RS00455	100079..100977	-	899	Protein_84	SDR family NAD(P)-dependent oxidoreductase	-
C2859_RS00460	101036..101773	-	738	WP_016849691.1	SDR family oxidoreductase	-
C2859_RS00465	101899..102810	+	912	WP_016849690.1	LysR family transcriptional regulator	-
C2859_RS00470	103007..104080	-	1074	WP_026006953.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11260.02 Da
• Isoelectric Point: 9.7235

>T93838 WP_005928957.1 NZ_CP026334:99592-99891 [Xanthomonas citri pv. glycines]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHIMRSERALRGNRLSR

Nucleotide

• Length: 300 bp

>T93838 NZ_CP026334:99592-99891 [Xanthomonas citri pv. glycines]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATCGAACACCCGGACAGCGGAAGCCGACCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGGTGGTGCACATCATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9674.20 Da
• Isoelectric Point: 9.8271

>AT93838 WP_016849693.1 NZ_CP026334:99347-99604 [Xanthomonas citri pv. glycines]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQARQRM
ARWLK

Nucleotide

• Length: 258 bp

>AT93838 NZ_CP026334:99347-99604 [Xanthomonas citri pv. glycines]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACGGCAACGCATG
GCGCGATGGCTGAAATAA

Structures

Antitoxin

• AlphaFold DB: A0A1D9ED60