93836

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3755212..3756095 Replicon chromosome
Accession NZ_CP026332
Organism Pseudomonas sp. XWY-1

Toxin (Protein)


Gene name - Uniprot ID Q88K57
Locus tag PRJ_RS17425 Protein ID WP_003250527.1
Coordinates 3755212..3755649 (-) Length 146 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID I7C3Q7
Locus tag PRJ_RS17430 Protein ID WP_003250525.1
Coordinates 3755646..3756095 (-) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PRJ_RS17410 3751509..3752738 - 1230 WP_104962077.1 acyl-CoA dehydrogenase -
PRJ_RS17415 3752879..3753805 + 927 WP_104962078.1 LysR family transcriptional regulator -
PRJ_RS17420 3754000..3755154 + 1155 WP_104962891.1 aminotransferase class V-fold PLP-dependent enzyme -
PRJ_RS17425 3755212..3755649 - 438 WP_003250527.1 RES family NAD+ phosphorylase Toxin
PRJ_RS17430 3755646..3756095 - 450 WP_003250525.1 DUF2384 domain-containing protein Antitoxin
PRJ_RS17435 3756238..3756891 - 654 WP_014591578.1 oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB -
PRJ_RS17440 3756995..3757918 + 924 WP_104962079.1 LysR family transcriptional regulator -
PRJ_RS17445 3757967..3758797 + 831 WP_003250518.1 AraC family transcriptional regulator -
PRJ_RS17450 3758849..3759433 + 585 WP_104962080.1 LysE family transporter -
PRJ_RS17455 3759473..3760672 - 1200 WP_104962081.1 sugar transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-138)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(33-91)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15990.29 Da        Isoelectric Point: 5.6007

>T93836 WP_003250527.1 NZ_CP026332:c3755649-3755212 [Pseudomonas sp. XWY-1]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPPGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSAQPELTRTLGNRFLDDCSALLLPVPSAIMPSTTNYLFNPRHPQAQSAKIQVEDFTPDSRLF

Download         Length: 438 bp

>T93836 NZ_CP026332:c3755649-3755212 [Pseudomonas sp. XWY-1]
GTGATTTTGTGGCGAATCAGCGCCTATGCAGACTTGAGCGGTACGGGGGGCTTGCGTGTAAGTGGCCGCTGGCATCAGGC
GGGTCGACCGGTGGTGTATGCCGCCACCAGCCCTCCCGGGGCGATGCTGGAAGTGTTGGTGCACCTGGAGATCGACCCCG
AGGATTTCCCTACCACCATGCGCTTGCTGCGCATCGAACTGCCCGACACGGTTTCCCAGGCGCAGTTGCCCGCTTTGCAG
CCCGGCTGGTCTGCTCAGCCTGAGTTGACCCGTACGCTGGGCAATCGCTTTCTGGATGACTGTTCGGCATTGCTGCTGCC
GGTGCCAAGCGCGATCATGCCCAGCACCACCAATTACCTGTTCAACCCACGGCACCCGCAGGCGCAGAGCGCGAAAATCC
AGGTTGAGGATTTCACGCCGGACAGCCGCCTGTTCTAG

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 16956.46 Da        Isoelectric Point: 5.7258

>AT93836 WP_003250525.1 NZ_CP026332:c3756095-3755646 [Pseudomonas sp. XWY-1]
MLAEVLRDNGYHEYRARLQALLDIPELASDFEIHTRITDGFAATWLVKLTERGVLTPVERDQIIPLRTLKSRIERDQPLT
VDESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGYGL

Download         Length: 450 bp

>AT93836 NZ_CP026332:c3756095-3755646 [Pseudomonas sp. XWY-1]
ATGCTTGCCGAAGTGCTTCGCGACAACGGTTACCACGAGTACCGGGCGCGCCTGCAGGCGCTGCTGGACATTCCCGAGCT
TGCCAGCGACTTCGAAATTCACACCCGCATCACCGATGGTTTTGCCGCCACCTGGTTGGTGAAGCTGACCGAGCGCGGTG
TGCTCACCCCGGTGGAGCGCGACCAGATCATTCCGCTGCGCACCCTCAAATCCCGTATCGAGCGCGACCAACCGCTGACC
GTGGATGAGAGCGATCGGCTGTTCCGCTCGGCCCACATCACCGCCATGGCCGAGGCCGTGTTCGGTGAAGCGGGCAAGGC
CAAACGCTGGCTTTCCAAGCCCAAGGAACGCTTCTCGGGGCTGACGCCGATGCAGATGCTCACCACCCAGCAAGGCACCA
CTCAGGTCGAAGAAATGCTGCTGCAGATTGCCGAGGGCTATGGCCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 6GW6

Antitoxin

Source ID Structure
AlphaFold DB I7C3Q7

References